Mature cystic teratoma in a 5-year-old girl presenting as urinary frequency: A case report / 대한산부인과학회지

Ovarian tumors are rare in children. Their incidence is estimated to be about 2.6 cases per 100,000 girls per year. About 1/3 of all childhood ovarian tumors are reported to be malignant. Germ cell tumors are more frequent than epithelial and sex cord stromal tumors in children and teratoma is the most common germ cell tumor occurring in children. In most cases, the presenting symptoms in childhood included abdominal pain, an abdominal mass, abdominal distention and so on. These non-specific symptoms and low incidence lead to suspicions of more common diseases, so the diagnosis of ovarian masses in childhood is difficult. We experienced a rare case of mature cystic teratoma in a 5-year-old girl with urinary frequency without abdominal discomfort despite the large size. The pre-operative magnetic resonance imaging finding showed unusual characteristics, rising suspicion of malignancy. So, we present this case with a brief review of literature.

A case of uterine angioleiomyoma causing severe anemia / 대한산부인과학회지

Angioleiomyoma is a benign mesenchymal neoplasm composed of smooth muscle cells and thick-walled vessels. It usually originates in the extremities or the head. Thus angioleiomyoma of the uterus is a very rare so that there were only 10 cases in the available English literature. Angioleiomyoma cause no serious problems with regard to diagnosis and are simply recognized as benign leiomyomas. These tumors happen to be found only after the surgery through histologic findings. It is therefore extremely difficult to diagnose angioleiomyoma by its shape through preoperative sonography test. We experienced a case of angioleiomyoma with massive vaginal bleeding causing severe anemia which seemed as a benign leiomyoma before the surgery. Hence, we report this case with a brief review of literature.

Malignant gestational trophobalstic tumor with markedly elevated serum hCG levels and negative urine hCG level / 대한산부인과학회지

Gestational trophoblastic disease comprises a spectrum of interrelated conditions originating from the placenta. Malignant gestational trophoblastic disease refers to lesions that have the potential for local invasion and metastasis. This compromises many histological entities including hydatidiform moles, invasive moles, gestational choriocarcinomas, and placental site trophoblastic tumors. Before the advent of sensitive assays for human chorionic gonadotropin (hCG) and efficacious chemotherapy, the morbidity and mortality from gestational trophoblastic disease were substantial. Currently, with sensitive quantitative assays for beta-hCG and current approaches to chemotherapy, most women with malignant trophoblastic disease can be cured. We present a case of malignant gestational trophobalstic tumor with serum beta-hCG concentration over 1million IU/L that metastaze to the lungs and have a hyperthyroidism, but negative urine hCG testing. We report a case with a brief review of literatures.