ABSTRACT
PURPOSE: We prospectively evaluated the diagnostic efficacy of the BTA TRAK assay according to the stage, grade and hematuria in detecting primary and recurrent bladder cancer, and compared results with voided urine cytology. MATERIALS AND MTHODS: Urinalysis, cytology and BTA TRAK assay were performed simultaneously with the single voided fresh urine samples from 130 subjects. The sensitivity and specificity of the BTA TRAK assay were compared to those of urine cytology and analyzed according to the stage or grade. The subjects were also divided into 4 groups according to the degree of hematuria and the influence of hematuria on the result of the BTA TRAK assay was evaluated. RESULTS: The overall sensitivity and specificity of the BTA TRAK assay for detecting bladder cancer were 82.8% and 65.3%, respectively and those of urine cytology were 44.8% and 100%. The sensitivity of the BTA TRAK assay was significantly higher than that of urine cytology in bladder cancer with lower stage and grade. On univariate and multivariate analysis, gross hematuria and the presence of bladder cancer affected the results of the BTA TRAK assay significantly. In cases following after transurethral resection of bladder tumor (TURB), the sensitivity and specificity of the BTA TRAK assay for detecting recurrent bladder cancer were 100% and 79.5%, respectively. CONCLUSIONS: The BTA TRAK assay was more sensitive but less specific than voided urine cytology. Because gross hematuria affected the result of the BTA TRAK assay independently, it appears reasonable to delay the BTA TRAK assay until gross hematuria subsides in cases with gross hematuria. In cases following after TURB, the BTA TRAK assay appears to be useful for detecting recurrent bladder cancer.
Subject(s)
Diagnosis , Hematuria , Multivariate Analysis , Prospective Studies , Sensitivity and Specificity , Urinalysis , Urinary Bladder Neoplasms , Urinary BladderABSTRACT
PURPOSE: We prospectively evaluated the diagnostic efficacy of the BTA TRAK assay according to the stage, grade and hematuria in detecting primary and recurrent bladder cancer, and compared results with voided urine cytology. MATERIALS AND MTHODS: Urinalysis, cytology and BTA TRAK assay were performed simultaneously with the single voided fresh urine samples from 130 subjects. The sensitivity and specificity of the BTA TRAK assay were compared to those of urine cytology and analyzed according to the stage or grade. The subjects were also divided into 4 groups according to the degree of hematuria and the influence of hematuria on the result of the BTA TRAK assay was evaluated. RESULTS: The overall sensitivity and specificity of the BTA TRAK assay for detecting bladder cancer were 82.8% and 65.3%, respectively and those of urine cytology were 44.8% and 100%. The sensitivity of the BTA TRAK assay was significantly higher than that of urine cytology in bladder cancer with lower stage and grade. On univariate and multivariate analysis, gross hematuria and the presence of bladder cancer affected the results of the BTA TRAK assay significantly. In cases following after transurethral resection of bladder tumor (TURB), the sensitivity and specificity of the BTA TRAK assay for detecting recurrent bladder cancer were 100% and 79.5%, respectively. CONCLUSIONS: The BTA TRAK assay was more sensitive but less specific than voided urine cytology. Because gross hematuria affected the result of the BTA TRAK assay independently, it appears reasonable to delay the BTA TRAK assay until gross hematuria subsides in cases with gross hematuria. In cases following after TURB, the BTA TRAK assay appears to be useful for detecting recurrent bladder cancer.
Subject(s)
Diagnosis , Hematuria , Multivariate Analysis , Prospective Studies , Sensitivity and Specificity , Urinalysis , Urinary Bladder Neoplasms , Urinary BladderABSTRACT
PURPOSE: Prostate biopsies were performed usually in patients with intermediate Prostate Specific Antigen (PSA) levels, however cancer detection rate was low. We would like to reduce unnecessary biopsies by developing a new PSA formula for determining cancerous conditions of the prostate. MATERIALS AND METHODS: We retrospectively enrolled 99 patients with intermediate serum PSA levels. The patients were divided into two groups, the prostate cancer group (19 patients) and the benign disease group (80 patients). We developed a new formula to calculate the age-adjusted PSA density (AAPSAD), and applied it to both groups. In addition, we compared the efficacy of AAPSAD in detecting prostate cancer in men with intermediate PSA levels, compared with other PSA parameters. RESULTS: The prostate cancer patients had higher AAPSAD than non-prostate cancer patients (p=0.000). The sensitivity, and specificity, of AAPSAD were 94.7% and 60.0%, respectively at a cut-off level of 0.6, and higher than those obtained for the Prostate Specific Antigen Density (PSAD), PSA density of the transitional zone (PSA-TZ) and free to total PSA ratio (F/T PSA ratio). CONCLUSIONS: We suggest that the use of AAPSAD, in patients with intermediate PSA levels, may be helpful, not only to detect prostate cancer, but also to reduce unnecessary prostate biopsies.
Subject(s)
Humans , Male , Biopsy , Prostate , Prostate-Specific Antigen , Prostatic Neoplasms , Retrospective Studies , Sensitivity and SpecificityABSTRACT
Primary renal malignant fibrous histiocytoma is a rare tumor of the kidney. It is clinically and radiologically indistinguishable from a renal cell carcinoma. Even following radical surgery, the tumor shows a strong predilection for local recurrence and the prognosis is generally poor. We report on a 32-year-old man with malignant fibrous histiocytoma of the kidney who remained free of recurrence for 1 year after radical nephrectomy.
Subject(s)
Adult , Humans , Male , Histiocytoma, Benign Fibrous/diagnosis , Kidney Neoplasms/diagnosis , Nephrectomy , Tomography, X-Ray ComputedABSTRACT
Primary renal malignant fibrous histiocytoma is a rare tumor of the kidney. It is clinically and radiologically indistinguishable from a renal cell carcinoma. Even following radical surgery, the tumor shows a strong predilection for local recurrence and the prognosis is generally poor. We report on a 32-year-old man with malignant fibrous histiocytoma of the kidney who remained free of recurrence for 1 year after radical nephrectomy.
Subject(s)
Adult , Humans , Male , Histiocytoma, Benign Fibrous/diagnosis , Kidney Neoplasms/diagnosis , Nephrectomy , Tomography, X-Ray ComputedABSTRACT
After pelvic trauma, complications of urethral stricture and organic impotence may develop. Certain cases of these are combined with penile curvature, which treatment method of artificial erection alone is not suitable, because severe penile pain may occur during erection, Therefore proper surgical methods should be added for straightening the penile curvature. After pelvic trauma, complete urethral stricture and organic impotence with penile curvature developed in 3 patients who complained severe pain due to curvature during the intracavernosal injection test. To all, treatment of choice for complete urethral sticture was visual internal urethrotomy for prevention of further development of curvature, and for curvature, Nesbit's penile straightening operations were performed, one by one. All patients could well urinate and enjoy their sexual intercourse after intracavernosal injection of PGE1 or papaverine. We recommend visual internal urethrotomy and the Nesbit's operation as effective methods to treat the case of penile curvature combined with complete urethral stricture after pelvic trauma.
Subject(s)
Humans , Male , Alprostadil , Coitus , Erectile Dysfunction , Papaverine , Urethral StrictureABSTRACT
Penile strangulation developed by wearing metallic or non-metallic objects is unusual but potentially serious. We report a case of 33-year-old man who presented with penile strangulation after applying the device for self-circumcision. The device was removed and after debridement of the infected necrotic tissues and antibiotic therapy, conventional circumcision was performed. It is stressed that circumcision should be performed by urologists.
Subject(s)
Adult , Female , Humans , Male , Circumcision, Male , Debridement , PenisABSTRACT
No abstract available.
ABSTRACT
Various intravesical foreign bodies have been reported in the literature. We report a rare case of intravesical newspaper that was self-introduced through the urethra as a means of masturbation. A 36 year old male patient was suffered from intermittent dysuria and gross hematuria due to self-inserted newspaper in the bladder. The clinical symptoms, diagnostic maneuvers and treatment of intravesical foreign bodies were described.