ABSTRACT
The effect of 0.25% and 0.5% Timolol on intraocular pressure and concentration in aqueous humor was studied after topical instillation in the white rabbit. The intraocular pressure was measured with pneuma tonometer and the Timolol concentration in aqueous humor was measured with High Preformance Liquid Chromatograph after fine needle aspiration of aqueous humor at various time intervals. The results were as follows; 1. The percentage reduction of intraocular pressure increased with time and reached a peak after 3 hours. 2. The concentration of Timolol in aqueous humor increased with time and reached a peak after 3 hours. 3. There was close correlation between intraocular pressure and Timolol concentration in aqueous humor.
Subject(s)
Aqueous Humor , Biopsy, Fine-Needle , Intraocular Pressure , TimololABSTRACT
Solitary choroidal tuberculoma is a rare ocular tuberculosis, a form of secondary infection derived through the blood-stream from some focus of infection elsewhere in the body, characterized by gradual growing until it resembles a tumor projecting into the cavity of eye. Authors experienced a case of a solitary choroidal tuberculoma. A brief review of literature is described.