Two Cases of Successful Clipping Closure of Iatrogenic Duodenal Perforation Occurred during Endoscopic Procedure / 대한소화기내시경학회지

The risk of complications associated with endoscopic procedures, including bleeding and perforation, tends to increase due to the magnification of the therapeutic endoscopic spectrum. In cases of duodenal perforation, surgical closure is the treatment of choice; however, there have been some cases in which the nonsurgical treatment of an iatrogenic duodenal perforation during an endoscopic procedure was effected via endoscopic clipping closure. Here, we report two cases of successful endoscopic clipping closure of an iatrogenic duodenal perforation occur ring during a duodenoscopy insertion for ERCP and endoscopic mucosal resection for the treatment of duodenal adenoma.

Short-term Result of Radiofrequency Catheter Ablation in Pediatirc Patients with Paroxysmal Tachycardia

PURPOSE: To find out the efficacy, safety and early complication of radiofrequency catheter ablation(RFCA) in pediatric patients with paroxysmal tachycardia, we compared short-term results of RFCA in pediatric patients to adult patients. METHODS: We studied 25 patients(11 pediatric patients, 14 adult patients), who underwent RFCA due to paroxysmal supraventricular tachycardia(PSVT) or idiopathic ventricular tachycardia(VT) from November 1997 to August 1998. We evaluated PSVT or idiopathic VT mechanism and compared total procedure times, total energy durations and complication rates between pediatric patients and adult patients. RESULTS: Among the 25 patients, the mechanisms of tachycardia were atrioventricular reentrant tachycardias in 14 patients, atrioventricular nodal reentrant in 10 patients and idiopathic left ventricular in 1 patient. Among the 11 pediatric patients, atrioventricular reentrant was found in 9 patients, atrioventricular nodal reentrant in 1 patient and idiopathic left ventricular in 1 patient. while among the 14 adult patients, atrioventricular reentrant was found in 5 patients and atrioventricular nodal reentrant in 9 patients. Total procedure time was 190+/-52 minutes in pediatric patients and 161+/-49 minutes in adult patients(P=0.17). Total energy duration was 244+/-223 seconds in pediatric patients and 187+/-122 seconds in adult patients(P=0.45). There were no major complications related to RFCA except minor hematomas at puncture sites. CONCLUSION: Considering the total procedure time, total energy duration and complication rates, there were no significant differences between pediatric patients and adult patients. RFCA showed relatively high success rate and one recurrence after initial success. Thus, we consider RFCA is as a good therapeutic modality which can cure tachycardia, especially PSVT.

Effect of Background Subtraction on Thallium-201 Kinetics in Myocardium : Comparison between Exercise and Pharmacologic Test with Adenosine, Dipyridamole, or Dobutamine

BACKGROUND: Quantitative myocardial perfusion scintigraphy with thallium-201 has provided an increase in accuracy of coronary artery disease detection. Myocardial uptake and clearance data based on thallium-201 kinetics in normal subjects is using in quantitative interpretation of myocardial perfusion scan. Exercise and pharmacologic stress make different hemodynamic effects and different myocardial uptake and clearance of thallium-201. Effect of background subtraction on thallium-201 myocardial perfusion scintigraphy may also be different due to different thallium-201 biokinetics in each type of stress used. This study was aimed to evaluate the effects of the background subtraction on myocardial thallium-201 biokinetics according to the type of stress used. METHODS: Fifteen healthy volunteers underwent planar thallium-201 myocardial perfusion imaging with peak treadmill exercise and intravenous infusion of dipyridamole, adenosine, or dobutamine. Each subject underwent another planar thallium-201 myocardial perfusion imaging at 4 hour later, as a redistribution imaging. Count densities from ROIs(regions of interest) drawn over left ventricle, lung, and liver were compared between before- and after background subtraction. RESULTS: Before background subtraction, absolute myocardial thallium-201 uptake was greater after pharmacologic testing than exercise testing in both stress and redistribution imaging. Myocardial thallium-201 clearance was lower during pharmacologic stress than exercise. After background subtraction, myocardial thallium-201 uptake was higher during exercise than pharmacologic testing. The percentage change in clearance was higher with exercise testing, while the percentage change in uptake was higher with pharmacologic testing. CONCLUSION: Thallium-201 uptake and clearance in heart and adjacent structure were different between adenosine, dipyridamole, dobutamine, and exercise testing. Background subtraction results in different myocardial uptake and clearance data due to different extracardiac uptake subtracted in each stress method. The diagnostic criteria for quantitative analysis of myocardial perfusion imaging must be specified for types of myocardial stress and processes used for background subtraction.