ABSTRACT
We retrospectively reviewed 48 pregnancies in 36 female patients after renal transplantation until February, 1998 at Yonsei University College of Medicine. All patients were maintained on cyclosporine-based immunosuppressive regimen before, during and after pregnancy. Patients were divided into two groups; group 1 (Delivery Group) of 25 women with 26 pregnancies and group 2 (Abortion Group) of 19 women with 22 pregnancies. Mean interval between renal transplantation and conception is 31.8+/- 22.9 months. Serum creatinine was reported before, during and after pregnancy and there was no significant changes of its mean value in both groups. Mean daily dosage of cyclosporine were similar in patients. Average gestational age was 37.0+/- 2.0 weeks and the incidences of very low birth weight (VLBW), low birth weight (LBW) and small for gestational age (SGA) were 7.7%, 63.5% and 84.6%, respectively. Pregnancy-related complications during pregnancy in group 1 were urinary tract infection in 11 cases, preeclampsia in 7 cases, hypertension in 4 cases and proteinuria in 3 cases. There was no acute rejection or graft loss during pregnancy. The premature deliveries less than 37 weeks were 12 cases (46.2%). Low birth-weight of neonate was significantly related with maternal pre-pregnant hypertension (1793.3+/- 393.0 gm in patients with hypertension vs. 2471.2+/- 468.1 gm in patients without hypertension; p=0.001). Pregnancy in female renal transplant patients is relatively safe while they are monitored in a tertiary care center with close monitoring of cyclosporine A (CsA) dosing, serum creatinine levels and the other laboratory values by a transplant surgeon, nephrologist, obstetrician and pediatrician.
Subject(s)
Female , Humans , Infant, Newborn , Pregnancy , Allografts , Creatinine , Cyclosporine , Fertilization , Gestational Age , Hypertension , Incidence , Infant, Low Birth Weight , Infant, Very Low Birth Weight , Kidney Transplantation , Mothers , Pre-Eclampsia , Proteinuria , Retrospective Studies , Tertiary Care Centers , Transplants , Urinary Tract InfectionsABSTRACT
Pulmonary sequestration is a relatively rare congenital anomaly in which a mass of abnormal pulmonary tissue without a normal connection to the tracheobronchial tree receives its blood supply from one or more anomalous systemic arteries. Its incidence increased as prenatal ultrasound become a routine component of prenatal care. We report one case of intra-abdominal extralobar pulmonary sequestration detected by prenatal ultrasound and diagnosed at surgery after birth.
Subject(s)
Arteries , Bronchopulmonary Sequestration , Incidence , Parturition , Prenatal Care , UltrasonographyABSTRACT
Since the identification of the C-group chromosome has been made possible by the introduction of banding technique, the features of the trisomy-8 syndrome have been defined. Most of them have been mosaics and have had similar clinical findings. A case of Trisomy-8 mosaicism confirmed by G-banding analysis by skin fibroblast and heart blood in a dead female fetus of 35 weeks of gestation is described.