Complications in cases of enteric perforation

Enteric perforation is a disastrous complication of untreated or poorly treated typhoid fever and unless treated by surgical method, it results in considerable morbidity and mortality. The purpose of this study to describe complications of ileostomy in patients of enteric perforation. The study was conducted was in surgical units B-V hospital, Bahawalpur from 1[st] July 2008 to 30[th] June 2009. This was a descriptive case series study. 100 patients of both genders suffering from typhoid fever with perforation who underwent ileostomy were included the study. All the data was collected on pre-designed proforma. Most of the patients were young with male to female ratio 1.6:1. Ileostomy was done in all the patients after cleaning the peritoneal cavity. Ileostomy was associated with diarrhea 20%, peristomal skin problems 22%. Other complications were bleeding in 3%,prolapsed in 5%, retraction in 4%, parastomal hernia in 5%, wound infection in 8%, intestinal obstruction in 5% patients, incisional hernia and psychological symptoms in 2% patients and stoma stenosis in one patient in our study. Two patients expired due the complication of ileostomy. Although ileostomy is not the most favored way of treatment of enteric perforation and it is associated with a number of complications and management problems, it is still a good option and life saving procedure in our setup where patients present very late with gross peritoneal contamination

Risk factors; comparison in hepatitis B and C carrier pregnant women and healthy pregnant women

To determine the risk factors associated with hepatitis B and C carriers versus healthy pregnant women. It was a single center based, cross sectional comparative study, conducted at Gynae ward II, B-V hospital Bahawalpur. Duration of study was from March to August 2008. 100 patients were enrolled in the two groups, 50 HbsAg/Anti HCV positive women [cases] to compare with 50 healthy women [controls] match for parity. The data were recorded on a proforma. 100 pregnant women were enrolled. Sixty eight [68.0%] were aged 25 years or less with a mean age +/- S.D of 24.62 +/- 3.40. Ten [20%] women had HBV and 40[80%] were HCV positive. The risk factors were compared between the two groups by uni-variate and multivariate analysis which showed that history of dental treatment, blood transfusion, surgery, parenteral treatment and jaundice were significant risk factors for hepatitis B and C carrier status. There appears to be a strong co-relation of history of blood transfusion and dental treatment with HbsAg/ Anti HCV carrier state in pregnant women. The anti HCV seropositivity was appreciably high [80%] as compared to HbsAg [20%] in carrier pregnant women