ABSTRACT
There had been contineous evolution in the understanding of etiology, pathogenesis and complications of diabetes since its discovery. Insulin is secreted by the B-cells of islets of Langnhan's and in IDDM there is marked reduction in the content of B-cells while in NIDDM, there is considerable reduction of its mass. The aim of this work was to study changes in pancreatic size in diabetic patients as detected by both U/S and CT studies. It was noted that there is considerable reduction in pancreatic size in those patients of IDDM group, while in NIDDM patients the size reduction was less marked and it was evident more in those under insulin therapy than those controled by oral hypoglycaemic drugs. The head was less affected than the body in NIDDM patients while in IDDM all segments were affected