ABSTRACT
24 amino acids were tested for inducing CPK activity within 40 selected members of entero-bacteriaceae as well as other pathogenic bacteria. Klebsiella remarkably produced the enzyme when incubated with any of the acids [1.7-5.4 U/10[7]/ ml] followed by the shigellae [0.2-1.5 U/10[7] cells/ml] then the vibrios [0.4-1.3 U] then Yersinia [0.4-0.5]. The tested arizonas, escherishias, erwinias or pseudomonas produced appreciable amounts of the enzyme only on one or few amino whereas the proteii as well as Salmonella farmsen failed to do so on any of the tested amino acids. The remaining salmonellas could release the enzyme in several of their amino acids media but S. paratyphi, S. sofia, S. typhi, S. typhimurium or S. wassenaar were the best producers on all tested amino acids [0.2-0.8 U]. Valine, arginine, iso-leucine or glycine was the most active CPK inducers [19-17 organisms the least [12-11 organisms]. The remaining amino acids were intermediate [16-14 organisms]