Frontal Garden index for the assessment of displacement degree of Garden type III femoral neck fracture and its clinical value / 中华创伤杂志

Objective:To discuss the displacement characteristics of Garden type III femoral neck fracture and investigate the reliability, validity and clinical value of the frontal Garden index in assessing the displacement degree of Garden type III femoral neck fracture.Methods:The pelvis X-ray films of 98 patients with Garden type III femoral neck fracture treated at Luoyang Orthopedic-Traumatological Hospital of Henan Province (Henan Provincial Orthopedic Hospital) from October 2010 to October 2018 were collected, including 47 males and 51 females; aged 19-89 years [(64.9±16.2) years]. Three-dimensional data of the hip with 64-slice CT were available in 21 patients. Each patient′s frontal Garden index was measured three times by three senior doctors, which was repeated twice in turn. The distribution characteristics of the frontal Garden index were statistically described. The reliability of the frontal Garden index was tested by Spearman correlation coefficient and Kappa coefficient, including test-retest reliability and intra-rater consistency. The contact area of fracture ends and upper-shift distance of the femoral neck were calculated based on three-dimensional CT data of the hip in 21 patients. Correlation analysis of the contact area of fracture ends and upper-shift distance of the femoral neck with the frontal Garden index was performed by multiple correlation analysis to assess the validity of the frontal Garden index.Results:The Frontal Garden index of 98 patients with Garden type III femoral neck fracture was (136±15) °, with the minimum value of 90 ° and maximum value of 159 °, and was found to be normally distributed ( P>0.05). Spearman correlation coefficient of the test-retest reliability was 0.93, 0.97 and 0.95, respectively (all P<0.01). Kappa coefficient of the intra-rater consistency was 0.87, 0.91 and 0.86, respectively (all P<0.01). The frontal Garden index was positively correlated with the contact area of fracture ends ( r=0.80, P<0.01), and was negatively with the upper-shift distance of the femoral neck ( r=-0.77, P<0.01). Conclusions:The displacement degree of Garden type III femoral neck fracture shows diversity and normal distribution. The frontal Garden index can credibly and effectively measure the displacement degree of Garden type III femoral neck fracture, which may help to choose the treatment plan.

Clinical features and treatment of coronary artery aneurysms / 中国医师进修杂志

Objective:To investigate the clinical characteristics and therapeutic methods of coronary artery aneurysm (CAA).Methods:The clinical data and coronary angiography of 32 patients confirmed by coronary angiography as coronary aneurysm in Shenzhen Hospital of Southern Medical University and Shenzhen People′s Hospital were collected. They were followed up, and the different therapeutic methods were analyzed.Results:Thirty-two cases (1.8%) of coronary artery aneurysms were found in 1 778 patients undergoing coronary angiography. The main sites of coronary ectasia were right coronary artery, anterior descending branch and circumflex branch, and the left main branch was rare. Among the patients with coronary artery aneurysms, there were 25 patients with coronary artery stenosis. All the 32 patients were given anticoagulant, antiplatelet, improvement of coronary spasm and statin therapy, among whom 2 patients were treated with stent implantation and 6 patients were treated with coronary artery bypass graft (CABG) and ligation of coronary aneurysm. During the follow-up (average 15 months) of 1 patient, acute myocardial infarction reoccurred, and coronary angiography indicated that the stenosed coronary segments after artery ectasia was occluded because of thromboembolism. In the remaining patients, there were no major cardiovascular events such as angina pectoris, acute myocardial infarction and sudden cardiac death.Conclusions:Coronary artery aneurysm is not a rare heart disease. Coronary thromboembolism, thrombosis and vasospasm are the main causes of angina pectoris and myocardial infarction. Anticoagulant, antiplatelet, antispasmodic drugs and suitable coronary artery bypass can significantly improve the clinical prognosis of patients with coronary artery aneurysm.

An iliac-crest-preserving iliac wing bone graft harvesting technique / 中华骨科杂志

Objective To evaluate the clinical application effects of an iliac-crest-preserving iliac wing bone graft harvesting technique and the bone regenerative ability of the donor site after harvesting.Methods From January 2016 to June 2017,a series of 39 patients including 28 men and 11 women aged between 16 and 59 y (35± 13 y in average) were prospectively collected to treat bone defects using the iliac-crest-preserving iliac wing bone graft harvesting technique.The patient cohort included 38 ipsilateral and 1 bilateral bone harvests taken from 15 femoral fracture non-unions,8 tibial fracture non-unions,11 femoral head necroses (hip preserving surgery),1 tuberculosis deriving hip arthritis with bone defect (total hip arthroplasty),2 hip prosthesis loosenings (revision),and 2 proximal femoral benign tumors.All patients were treated through comprehensive surgeries containing autologous iliac bone grafting.The surgical time,blood loss,bone graft volume,24 h post-operative visual analogue scale (VSA) at the iliac surgical site,complications,and bone regeneration of the donor site were documented and evaluated.Results In the 39 patients (40 sides),the average surgical time was 25±4 min,average blood loss was 79±23 ml,average bone graft volume was 27±6 cm3.The average 24 h post-operative VAS at the iliac surgical site was 1.8±0.7 points.The VSA at the 6 week later and thereafter were 0 in all patients.The iliac incisions in 38 patients (39 sides) were healed uneventfully.However,seroma at the iliac surgical site emerged in 1 patient at the 6th post-operative day in the manner of serous exudation and was treated successfully with non-operative measures.None infections and lateral femoral cutaneous nerve injuries took place.Iatrogenic non-displaced iliac crest fractures happened in the very first 2 patients when taking the crest as a pivot to pry up the graft,which united without special cure at the 3 month post-operative.This complication was completely avoided when shifting the pivot to the anterior pillar containing the anterior iliac spines.None pelvic fractures and heterotopic ossifications took place.Post-operative radiographical examinations revealed that the bone defects at the donor site shrank through bone regeneration,that mamillary or canine-tooth-shaped bone formation occurred in some of the cases,and that none complete bone regeneration took place to eliminate the bone defect at the donor.There were 12 patients in whom pre-and post-operative computed tomographic scans necessitated by the disease were prescribed,which facilitated the measuring of the bone defect at the donor site.The measurement of 13 sides revealed that the bone defects were decreased more or less:the average immediate post-operative bone defect was 25.7±6.5 cm2,the average 12 month post-operative bone defect was 12.7±5.3 cm2.Conclusion The iliac wing bone graft harvesting technique suggested here is safe and less invasive,in the premise of preserving the iliac crest and retaining the figure of the surgical site,it can harvest a large amount of iliac wing bone graft and reserve the bone regenerative ability of the donor site.

An efficient way to orientate S1 iliosacral screw guide-pin verified by CT / 中华创伤骨科杂志

Objective To introduce an efficient way to orientate S1 iliosacral screw guide-pin verified by CT.Methods The pelvic axial CT data in DICOM format of 180 adults between July 2017 and June 2018 were retrieved from the database of Imaging Center,Luoyang Orthopaedic Hospital of Henan Province.The data were input into the software Mimics 20.0 to display the axial,coronal and sagittal sectional views of the pelvis.On the axial CT sectional view displaying the largest osseous pathway in the S1 segment,a virtual iliosacral screw and its virtual guide-pin were accurately placed into the sacral body in an oblique fashion.In the design of ideal insertion,the virtual screw and guide-pin were truly in the pelvic transverse plane when they were located exactly in the pelvic axial CT sectional view,and they intersected the outer iliac table at the start-point which restricted the guide-pin's location,and angulated with the pelvic coronal plane (represented by a line connecting the most dorsal points of bilateral ilia) at an angle (α) which limited the guide-pin's orientation.After three-dimensional pelvic models of the standard lateral sacral view and the pelvic outlet and inlet views in each patient were calculated,they were displayed in a transparent manner using the software,followed by the virtual insertion of the screw and guide-pin.After the start-point was established on the standard lateral sacral view,the guide-pin was orientated into the pelvic transverse plane and at the guide-pin's α angle relative to the pelvic coronal plane,and subsequently inserted into the ilium shallowly for stabilization.The pelvic outlet and inlet views were taken to judge the guide-pin's orientation.If fine orientation was verified,the guide-pin was advanced to its final position,followed by virtual insertion of an iliosacral screw over the guide-pin.After the virtual insertion was completed,the axial,coronal and sagittal CT sectional views of the pelvis were scrutinized to evaluate the accuracy of insertion.Results After all the guide-pins were orientated in the 180 adults (360 sides) on the true sacral lateral view according to the above way,their orientations on the pelvic outlet and inlet views were 100％ fine,leaving further adjustment unnecessary.The intraosseous insertions of the virtual screws and guide-pins were 100％ accurate and safe on the CT sectional images.Conclusion The way introduced here can theoretically guarantee accurate orientations of the guide-pin on the pelvic outlet and inlet views with no more complex guide-pin adjustments,assuring insertion accuracy and enhancing surgical efficiency.

An iliac-crest-preserving iliac wing bone graft harvesting technique / 中华骨科杂志

Objective@#To evaluate the clinical application effects of an iliac-crest-preserving iliac wing bone graft harvesting technique and the bone regenerative ability of the donor site after harvesting.@*Methods@#From January 2016 to June 2017, a series of 39 patients including 28 men and 11 women aged between 16 and 59 y (35±13 y in average) were prospectively collected to treat bone defects using the iliac-crest-preserving iliac wing bone graft harvesting technique. The patient cohort included 38 ipsilateral and 1 bilateral bone harvests taken from 15 femoral fracture non-unions, 8 tibial fracture non-unions, 11 femoral head necroses (hip preserving surgery), 1 tuberculosis deriving hip arthritis with bone defect (total hip arthroplasty), 2 hip prosthesis loosenings (revision), and 2 proximal femoral benign tumors. All patients were treated through comprehensive surgeries containing autologous iliac bone grafting. The surgical time, blood loss, bone graft volume, 24 h post-operative visual analogue scale (VSA) at the iliac surgical site, complications, and bone regeneration of the donor site were documented and evaluated.@*Results@#In the 39 patients (40 sides), the average surgical time was 25±4 min, average blood loss was 79±23 ml, average bone graft volume was 27±6 cm3. The average 24 h post-operative VAS at the iliac surgical site was 1.8±0.7 points. The VSA at the 6 week later and thereafter were 0 in all patients. The iliac incisions in 38 patients (39 sides) were healed uneventfully. However, seroma at the iliac surgical site emerged in 1 patient at the 6th post-operative day in the manner of serous exudation and was treated successfully with non-operative measures. None infections and lateral femoral cutaneous nerve injuries took place. Iatrogenic non-displaced iliac crest fractures happened in the very first 2 patients when taking the crest as a pivot to pry up the graft, which united without special cure at the 3 month post-operative. This complication was completely avoided when shifting the pivot to the anterior pillar containing the anterior iliac spines. None pelvic fractures and heterotopic ossifications took place. Post-operative radiographical examinations revealed that the bone defects at the donor site shrank through bone regeneration, that mamillary or canine-tooth-shaped bone formation occurred in some of the cases, and that none complete bone regeneration took place to eliminate the bone defect at the donor. There were 12 patients in whom pre- and post-operative computed tomographic scans necessitated by the disease were prescribed, which facilitated the measuring of the bone defect at the donor site. The measurement of 13 sides revealed that the bone defects were decreased more or less: the average immediate post-operative bone defect was 25.7±6.5 cm2, the average 12 month post-operative bone defect was 12.7±5.3 cm2.@*Conclusion@#The iliac wing bone graft harvesting technique suggested here is safe and less invasive, in the premise of preserving the iliac crest and retaining the figure of the surgical site, it can harvest a large amount of iliac wing bone graft and reserve the bone regenerative ability of the donor site

Percutaneous piercing cortical bone at fracture ends and local injection of autologous concentrated bone marrow aspirate and platelet rich plasma for treatment of delayed fracture union / 中华创伤骨科杂志

Objective To evaluate the clinical efficacy of percutaneous piercing cortical bone at fracture ends and local injection of autologous concentrated bone marrow aspirate (cBMA) and platelet rich plasma (PRP) in the treatment of delayed fracture union.Methods A retrospective study was performed on the clinical data of 34 patients with delayed fracture union who had been treated at Department of Orthopaedics,Luoyang Zhenggu Hospital of Henan Province from April 2014 to February 2017.They were 26 males 8 females,aged from 18 to 63 years (average,36.7 years).There were 15 femoral,11 tibial,5 humerus and 3 ulnar fractures.According to the Weber-Crech classification,14 cases belonged to the type of rich blood supply-active end hypertrophy and 20 to the type of poor blood supply and malnutrition.There were 28 closed and 6 open fractures.Of this cohort,21 cases had their primary fixation,7 had revision once,4 had revision twice,and 2 had revision more than thrice;19 cases had intramedullary fixation,12 had plate fixation and 3 had external fixation.Autologous iliac bone grafting was performed previously in 19 cases.Kirschner wire was used under fluoroscopy to pierce percutaneously the cortical bone at fracture ends;bone marrow blood and peripheral venous blood were collected to prepare autologous cBMA and PRP which were to be injected locally at the fracture ends after mixture.At the last follow-up,the patients were evaluated by visual analogue scale (VAS),SF-36 health survey summary scores and modified Radiographic Union Score for Tibia (RUST).Results The patients were followed up for 12 to 42 months (average,21.5 months).Thirty-one patients healed after surgery,yielding a healing rate of 91.2％.The healing time averaged 5.3 months (from 4 to 10 months).No patient reported such complications as infection or neurovascular injury.At the last follow-up,the VAS scores of the 34 patients were 1.3 ± 0.6 points,significantly lower than the preoperative 5.4 ± 3.6 points (P ＜ 0.05);the postoperative SF-36 scores 74.8 ± 16.5 points,significantly increased than the preoperative 44.8 ± 15.6 scores (P ＜ 0.05);the RUST scores 3.3 ± 0.4 points,significantly higher than the preoperative 1.6 ± 0.8 points (P ＜ 0.05).Conclusions Minimally invasive percutaneous piercing of K-wire on the cortical bone at the fracture ends may result in fluid leakage and restart bone healing process.At the same time,local injection of autologous cBMA and PRP may increase the number and concentration of local bone marrow mesenchymal stem cells and growth factors,promoting fracture healing.

Modified percutaneous retrograde intramedullary screwing into superior pubic ramus or anterior acetabular column for pelvic and acetabular injury / 中华创伤骨科杂志

Objective To evaluate the safety and accuracy of modified percutaneous retrograde intramedullary screwing into the superior pubic ramus or anterior acetabular column for pelvic and acetabular injury.Methods A retrospective analysis was conducted of the 23 patients with pelvic and acetabular injury who had been treated with modified percutaneous retrograde intramedullary screwing into the superior pubis ramus or anterior acetabular column from June 2015 to June 2017 in Luoyang Orthopaedic Hospital of Henan Province.They were 12 men and 11 women,aged from 22 to 88 years (mean,53 years).The injury included 17 pelvic fractures,4 acetabular fractures,and 2 acetabular plus pelvic fractures.The safety and accuracy of screwing were assessed by postoperative physical and imaging examinations.The number of fluoroscopy and operative time were documented for each retrograde intramedullary screwing into the pubic symphysis or acetabular anterior column.The quality of fracture reduction was evaluated by the Mata criteria postoperatively.The Majeed and the Harris scores were used to evaluate the functional recovery of the pelvis and acetabulum at the last follow-ups.Results A total of 31 intramedullary screws were placed in the 23 patients.For insertion of one screw,the operative time ranged from 15 to 50 min (average,35 min) and the number of fluoroseopy from 32 to 55 times (average,45 times).Postoperative physical examinations revealed no iatrogenic neurovascular lesion and uneventful healing of incisions in all the patients.Postoperative imaging examinations showed that 29 screws were located completely in the bone and 2 ones protruded the cortical bone of the pubic anterior border;all the screws did not protrude into the acetabulum or broke through the pubic symphysis or the pubic cortex.By the Matta criteria,the postoperative fracture reduction was rated as excellent in 17 cases,good in 5 and fair in one,giving an excellent to good rate of 95.7％.Of this series,19 were followed up for 6 to 24 months (mean,13 months).All the fractures healed after 3 months.The Majeed scores at the last follow-up for the 13 patients with pelvic fracture were excellent in 12 and good in one.The Harris scores at the last follow-up for the 6 patients with acetabular fracture (including the 2 with pelvic fracture) were excellent in 5 and fair in one.Conclusion The modified percutaneous retrograde intramedullary screwing into the superior pubic ramus or anterior acetabular column is safe,convenient and precise,effectiyely reducing radiation and operative time.

Femoral neck fractures fixed with intramedullary cannulated screws: factors for postoperative functional recovery / 中国组织工程研究

BACKGROUND: Hip arthroplasty and internal fixation with intramedullary cannulated screws are mainly used for senile femoral neck fractures. However, osteoporosis can usually lead to failure in internal fixation.OBJECTIVE: To analyze the joint function after fixed with intramedullary cannulated screws in elderly patients with femoral neck fractures, and to explore the factors related to functional recovery.METHODS: Clinical data of 89 patients with femoral neck fractures undergoing internal fixation with intramedullary cannulated screws after 2-year follow-up were analyzed retrospectively. The sex, age, Garden type, bone mineral density, body mass index, screw distribution, reduction index, operation time, bearing time and Harris hip scores were analyzed. Rank related analysis and accumulative Logistic regression analysis were performed on SPSS18.0 software. RESULTS AND CONCLUSION: (1) Normal Q-Q plot and normality test results indicated that the Horris scores in all patients after 2-year follow-up presented with skewed distribution (P=0.000). (2) Rank related analysis showed that age,Garden type, bone mineral density, and reduction index were related with Harris score (P < 0.05 or P < 0.01). (3) Accumulative Logistic regression analysis showed that the independent variables including age, Garden type, bone mineral density, and reduction index made significant effect on Harris hip scores. (4) To conclude, age, Garden type,bone mineral density, and reduction index are important factors for functional recovery of the hip after fixed with intramedullary cannulated screws.

Screening and verification of miRNAs differentially expressed in traumatic femoral head necrosis / 中华创伤骨科杂志

Objective To identify the plasma miRNAs which are differentially expressed in the patients with traumatic avascular necrosis of the femoral head by means of high-throughput screening so as to provide data for further research into the pathogenesis of traumatic avascular necrosis of the femoral head.Methods We selected 10 patients with femoral neck fracture who had been treated from January to April 2015 for traumatic avascular necrosis of the femoral head following manual reduction and internal fixation with percutaneous hollow screws (necrosis group) and another contemporary age-matched 10 patients with femoral neck fracture who had been treated in the similar way but did not develop traumatic avascular necrosis of the femoral head for over 2 years (control group).After the peripheral blood was obtained from the 20 patients,Axon GenePix 4000B chip scanner was used for peripheral blood chip screening to identify the miRNAs which were differentially expressed.QPCR technique was used to verify the top 5 miRNAs which were significantly up-regulated and the top 5 miRNAs which were significantly down-regulated.Results The Harris score for the necrosis group was significantly lower than that for the control group while the Visual Analog Scale score for the former significantly higher than that for the latter (P ＜ 0.05).There were no significant differences between the 2 groups in general data (P ＞ 0.05).In comparison of the 2 groups,the chip screening identified 95 miRNAs which were significantly up-regulated and 413 miRNAs which were significantly down-regulated.The "volcano" analysis screened out 147 miRNAs differentially expressed of which 35 were up-regulated genes and 112 down-regulated genes.Of the 10 genes selected,8 were found in line with the results of microarray screening:hsa-miR-93-5p,hsa-let-7i-5p,hsa-miR-320a,hsa-miR-25-3p,hsa-miR-16-2-3p,hsa-miR-122-5p,hsa-miR-4711-3p and hsa-miR-3191-5p.Conclusion This study indentified 8 differentially expressed miRNAs associated with traumatic osteonecrosis of the femoral head,providing data for further study.

Amelioration of biomechanical property of cortical bone in osteoporotic model rats with the kidney tonifying compound of traditional Chinese medicine / 中国组织工程研究

BACKGROUND: The biomechanical property(BP) of the bone is decided by its geometric structure and component material. Merely pursuing increase of the bone mineral density(BMD) might lead to deterioration of bone BP.However at present, some researohes on therapeutic action on osteoporosis emphasize excessively medical influence to BMD, and the change in the holistic BP of the bone in osteoporotic zone and its mechanism still need to investigate deeply.OBJECTIVE: To probe into the action and its mechanism of "the kidney tonifying compound of the Traditional Chinese Medical (TCM) "on BP of cortical bone in ovariectomized osteoporotic model rats.DESIGN: Completely randomized controlled experiment based on experimental animals.SETTING: Laboratory of Biomedical Engineering, Luoyang Hospital and Institute of Traditional Chinese Orthopedics and Traumatology in Henan Province.MATERIALS: The experiment was completed from November 2000 to July 2001 at Research Laboratory of Biomedical Engineering,Luoyang Institute of Traditional Chinese Orthopedics and Traumatology of Henan Province. The healthy Wistar female rats aged 10 months,weighing(350±20) g.METHODS: Fifty Whistar female rats aged 10 months were randomly divided into 5 groups: the normal, model, premarin-treated, xianling gubao-treated and migu capsule-treated with 10 in each group. The normal group was only given sham operation and the other four groups were ovariectomized. The rats after operation were fed normally for ninety days.Since the 91st day after operation,the rats had been given the medicines for 90 days and then killed. The thighbones were taken out,then BMD,femoral geometry sizes and BP were determined.MAIN OUTCOME MEASURES: ① The primary sequel was the comparison of the parameters of femoral BP. ② The secondary sequel was the changes in parameters of femoral geometric structure, area of cortical bone and BMD of every midsectional fomur.RESULTS: Femoral BP worsened significantly,its mechanical intensity reduced,its external diameter diminished,cortical bone area decreased and femoral BMD lowered in osteoporotic model rats. In comparison with the above,in "the kidney tonifying compound ofTCM " groups(migu capsule group and xianling gubao group) femoral BP raised significantly, its mechanical intensity advanced,its external diameter augmented,cortical bone area aggrandized and femoral BMD enhanced.CONCLUSION: "The kidney tonifying compound of TCM" can improve BP of the cortical bone(thighbone) in ovariectomized osteoporosis rats. Its primary mechanism of action is that the TCM compound prescription could enhance"the mechanism of biomechanical response and regulation"(MBRR) of macrostructure of cortical bone,consequently increase femoral external diameter,aggrandize cortical bone area and enhance BMD in ovariectomized rats.

Clinical and angiographic follow-up observation of sirolimus-eluting stents in the treatment of acute myocardial infarction / 中国介入心脏病学杂志

Objective To investigate the safety and effectiveness of sirolimus-eluting stents (SESs, Cypher stents) in the treatment of acute myocardial infarction. Methods Ninety seven SESs were implanted in 78 lesions of 78 patients with acute myocardial infarction. In all the lesions, 20.7% of the target vessel diameter ≤2.5 mm, 26% was in-stent restenosis, 82.3% was total occlusions lesions and 17.7% with degree of stenosis up to 95%. The in-hospital procedural success rate and the incidence of complications were observed. Major adverse cardiac events, restenosis rate and late lumen loss were also observed during follow-up. Results All stents were implanted successfully. There were no remained stenosis and major in-hospital complications. During clinical follow-up of 6-15 months (mean 10?3.6 months), 2 patients had recurrent angina due to in-stent restenosis confirmed by angiography, and required target vessel revascularization. No major adverse cardiac events was found in the other 76 patients, and the mortality was null. Follow up quantitative coronary angiographies were obtained in 64 patients, 9?2.2 months after the procedure. The average late lumen loss were 0.24?0.05 mm at the proximal edge, 0.19?0.03 mm within the stent segment, and 0.10?0.02 mm at the distal edge. The angiographic in-lesion restenosis rate was 3.1% and target vessel revascularization was 2.6%. Conclusion SES may be safe and feasiable for the treatment of acute myocardial infarction through reduction in restenosis and target vessel revascularization at 9 months after intervention.

Comparative study of clinical and angiographic follow-up of sirolimus-eluting stent and Pixel stent for treatment of coronary small vessel disease / 中国介入心脏病学杂志

Objective To compare the safety and efficacy of sirolimus-eluting stents (SES) and Pixel stents (PS) for treatment of coronary small vessel disease. Methods From March 2003 to January 2005, 67 patients with coronary small vessel disease were randomly divided into two groups: group A (n=34) and group B (n=33). Group A was treated with SES and group B with PS. The procedural success rate, major adverse cardiac events, restenosis rate and late lumen loss were compared between two groups. Results Procedural success rate in both groups was 100% without remained stenosis and cardiac complications. There were 30 patients in group A and 29 in group B whose quantitative coronary angiography was obtained 9 months after the procedure. Two patients in group A had recurrent angina because of in-stent restenosis, and 6 out of 7 patients with the angina in group B had angiographic evidence of in-stent restenosis. No death occurred in both groups during clinical follow-up. Angiographic restenosis rate was 6.7% in group A and 20.7% in group B (P

Coronary artery aneurysm and its clinical analysis / 中国介入心脏病学杂志

Objective To study the incidence of coronary artery aneurysm (CAA) in patients under coronary angiography (CAG), its clinic features and prognosis Methods Retrospective studies were conducted of the clinical features, treatment and outcome of 2?876 patients under CAG Results Among the 2?876 patients, 26 had CAA, the total incidence of CAA was 0 904% Among these patients, 14 had myocardial infarction, and 24 had narrowing coronary artery (stenosis≥50%) Among the 26 cases of CAA, 20 ateries had thrombosis No CAA had ruptured Conclusion The incidence of CAA in the studied CAG population was 0 904%, CAA could be responsible for myocardial ischemia and myocardial infarction