Case-control study on single locking plate and locking plate with suture anchors for the treatment of unstable distal clavicle fractures / 中国骨伤

OBJECTIVE@#To compare therapeutic effects of single locking plates and locking plates with suture anchors in treating type Neer IIb distal clavicle fractures.@*METHODS@#From January 2013 to January 2015, 40 distal clavicle fractures patients with Neer IIb were treated by retrospectively analyzed and divided into single locking plates (control group) and locking plates with suture anchors(observation group) according to methods of operation. There were 20 patients in control group treated by single locking plates, including 16 males and 4 females aged from 26 to 64 years old with an average of(40.60±12.64) years old; while there were 20 patients in observation group treated by locking plates with suture anchors, including 15 males and 5 females aged from 20 to 57 years old with an average of(37.30±10.56) years old. Length of incisions, operation time, blood loss, hospital stays, fracture healing observed by X-ray, position of internal fixation, and changes of coracoclavicular distance were compared, Constant-Murley score was used to evaluate shoulder joint function.@*RESULTS@#All patients were followed up from 22 to 42 months with an average of (30.08±6.72) months. There was no statistical significance in length of incisions, operation time, blood loss, hospital stays and fracture healing time (>0.05). Constant-Murley score in control group was 83.10±5.81, and lower than that of observation group (92.30±6.05)(<0.05) at final following-up. Coracoclavicular distance in control group (11.22±3.85) mm, was longer than that of observation group (8.71±2.14) mm(<0.05).@*CONCLUSIONS@#Compared with locking plates, locking plates with suture anchors for type Neer IIb distal clavicle fractures has better shoulder joint, shorter coracoclavicular distance. It showed coracoclavicular ligament is an effectiveness method for treating Neer IIb distal clavicle fractures.

Relationship between Iodine Content in Household Iodized Salt and Thyroid Volume Distribution in Children / 生物医学与环境科学（英文）

<p><b>OBJECTIVE</b>To assess the effect of different levels of salt iodine content on thyroid volume (ThV) distribution using data from the 1999, 2011, and 2014 Chinese national iodine deficiency disorder (IDD) surveys.</p><p><b>METHODS</b>Probability proportion to size (PPS) sampling method was used to obtain a representative national sample of 34,547, 38,932, and 47,188 Chinese children aged 8-10 years in 1999, 2011, and 2014 Chinese national IDD surveys, respectively. The iodine content in household iodized salt and urinary iodine concentration were measured and thyroid ultrasound examination was performed. The data were analyzed by SAS software using histograms and box plots. The skewness and kurtosis were calculated for testing the normality of ThV.</p><p><b>RESULTS</b>The median iodine content in household iodized salt dropped from 42.30 mg/kg in 1999 to 25.00 mg/kg in 2014. The median urinary iodine concentration of children aged 8-10 years decreased from 306.0 μg/L in 1999 to 197.9 μg/L in 2014. The median and interquartile range (IQR) of ThV in 1999, 2011, and 2014 surveys were 3.44 mL and 1.50 mL, 2.60 mL and 1.37 mL, 2.63 mL and 1.25 mL, respectively. The skewness and kurtosis of ThV distribution in 1999, 2011, and 2014 surveys were 1.34 and 5.84, 0.98 and 3.54, 1.27 and 5.49, respectively.</p><p><b>CONCLUSION</b>With reduced salt iodization levels, the median urinary iodine concentration and median ThV of children decreased significantly, and the symmetry of the ThV distribution improved.</p>

Relaxation laryngoplasty in the management of mutational falsetto / 中华耳鼻咽喉头颈外科杂志

<p><b>OBJECTIVE</b>To observe the result of relaxation laryngoplasty in the management of mutational falsetto.</p><p><b>METHODS</b>The thyroplasty type 3 was applied and improved (the saturation was improved in the traditional operation, which the thyroid cartilage stick was cut off and overlapped without saturation in improved group 1, while the thyroid cartilage stick was not cut off and overlapped inward without saturation in improved group 2) in 30 adult patients who failed in voice modification. Preoperative and postoperative fundamental frequency (F0), normalised noise energy (NNE) and reading essay were compared.</p><p><b>RESULTS</b>F0 dropped significantly from the preoperative mean of (276.5 +/- 46.7) Hz [see equation in text] to the postoperative mean of (127.5 +/- 32.1) Hz in one month (t = 13.68, P < 0.001), while the NNE dropped significantly from the preoperative mean of (-10.9 +/- 4.9) dB to the postoperative mean of (-7.7 +/- 4.1) dB, the difference was statistically significant (t = 4.07, P < 0.001). In the three kinds of operation, the postoperative F0 in the improved group 1 dropped most significantly (compared with traditional operation group t = 2.64, P< 0.05). The postoperative NNE in the improved group 2 increased minimally. The difference was not significant statistically compared with other two kinds of operations (P > 0.05). The pitch dropped in all cases during reading aloud and conversation, while the voice breaks was disappeared.</p><p><b>CONCLUSIONS</b>Relaxation laryngoplasty was proved to be an efficient procedure in the surgical management of mutational falsetto.It was a preferable option for the patients who failed in voice modification. The improved operation profited to recover natural intonation and lighten the hoarseness due to glottic incompetence.</p>

The study of tissue-engineering bone for repair of segmental bone defects / 中华整形外科杂志

<p><b>OBJECTIVE</b>To investigate the effect of tissue-engineering bone on repair of segmental bone defects.</p><p><b>METHODS</b>Segmental bone defect of 21mm was created at sheep left metatarsus, which was then implanted with tissue-engineering bone (the experimental group) and pure porous beta-TCP (the control group) respectively. The bone defect in the blank group was left without treatment. After the sheep were sacrificed at the 1st, 3rd, or 6th month postoperatively, the samples were taken and examined by radiological, histological and biomechanical methods as well as scanning electron microscopy. The sheep in the blank group were sacrificed at the 6th month postoperatively.</p><p><b>RESULTS</b>The osteoid tissue, woven bone and lamellar bone in the defect of the experimental group occurred earlier than in the control group. The new bone formed directly without through a cartilaginous intermediate in the experimental group, while the defect was repaired in a "creep substitution" way in the control group. At the 6th month, radiological and biomechanical tests revealed nearly complete repair of the bone defect of the experimental group, partial repair in the control group and non-healing in the blank group.</p><p><b>CONCLUSIONS</b>Tissue-engineering bone can repair bone defect, accelerating healing and without "creep substitution", which is a good option in repair of critical segmental bone defects. This study set up a basis for clinical applications in the future.</p>