ABSTRACT
Lipid metabolism disorder is an important risk factor to obesity, hyperlipidemia and type 2 diabetes as well as other chronic metabolic disease. It is also a key target in preventing metabolic syndrome, chronic disease prevention. Plant polyphenol plays an important role in maintaining or improving lipid profile in a variety of ways. including regulating cholesterol absorption, inhibiting synthesis and secretion of triglyceride, and lowering plasma low density lipoprotein oxidation, etc. The purpose of this article is to review the lipid regulation effects of plant polyphenols and its related mechanisms.
Subject(s)
Animals , Humans , Lipid Metabolism , Metabolic Diseases , Drug Therapy , Metabolism , Polyphenols , PharmacologyABSTRACT
As antibiotic drug resistance has become one of the most serious threats to global public health, there is a pressing need to look for new effective therapeutic drugs. Flavonoids are a large class of chemicals widely exist in plants, and have such effects as direct antibiotics, synergistic antibiotics and inhibition of bacterial activity. In this article, we made a summary for the advance in studies on the antibacterial effects of flavonoids and their mechanism.
Subject(s)
Animals , Humans , Anti-Bacterial Agents , Chemistry , Pharmacology , Bacteria , Drug Synergism , Flavonoids , Chemistry , PharmacologyABSTRACT
<p><b>OBJECTIVE</b>To study the chemical constituents of the twigs of Morus atropurpurea.</p><p><b>METHOD</b>The compounds of the EtOAc fraction were isolated and purified by column chromatography on silica gel, polyamide, Sephadex LH -20, and their structures were elucidated on the basis of spectroscopic evidence (MS, NMR).</p><p><b>RESULT</b>Eleven compounds were identified as mulberrin (1), cyclomulberrin (2), morusin (3), cyclomorusin (4), 2', 4',4, 2"-tetrahydroxy-3'-{3"-methylbut-3"-enyl-}-chalcone (5), mulberrofran G (6), scopoletin (7), moruchalcone A (8), kaempferol (9), ursolic acid (10), beta-daucosterol (11).</p><p><b>CONCLUSION</b>Except compounds 9 and 11, all the other compounds were obtained from M. atropurpurea for the first time.</p>