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@#Abstract: Objective To analyze the occupational hazards of enterprises in Pingshan district of Shenzhen in 2017. Methods Occupational hazards were analyzed in 200 enterprises in Pingshan district of Shenzhen City selected using stratified Results random sampling method. A total of 24 industries were involved in the 200 enterprises. The declaration rate of ， occupational hazards was 91.5% and the exposure rate of occupational hazards among workers was 49.2%. The regular monitoring rate of occupational hazard factors in workplaces of the enterprises was 79.5%. There were 129 kinds of occupational ， ， hazard factors of which 19 factors exceeded the national occupational exposure limit accounting for 14.7%. The over standard ， ， ， ， ， ， ， ， rates of noise silica dust cotton dust methanol toluene and other dust were 28.7% 13.6% 11.8% 5.86% 0.5% and ， ， 0.4% respectively. There were 13 kinds of occupational hazard factors in the workplace of metal products industry all of which （ ） exceeded the occupational exposure limit. The exposure rate 56.7% of occupational hazard factors in workers was the highest. Conclusion ， ， The main occupational hazard factors were noise dust and chemical factor and the major occupational hazard industry was metal manufacturing in Pingshan district of Shenzhen City.
ABSTRACT
Objective:To observe the effect of modified Shaofu Zhuyutang combined with Zheng's Rebuzhen therapy on pain caused by adenomyosis (cold coagulation and blood stasis syndrome) and levels of vascular endothelial growth factor (VEGF), matrix metalloproteinases-9 (MMP-9), tissue inhibitors of matrix metalloproteinases (TIMP-1) and prostaglandin. Method:One hundred and twenty-eight patients were randomly divided into control group (63 cases) and observation group (65 cases) by random number table. Patients in control group got desogestrel and ethinylestradiol tablets since the first day of menstruation for consecutive 21 days, 1 granule/time, 1 time/day, and Zheng's Rebuzhen therapy for consecutive 10 days during the menstruation, 1 time/day. In addition to the therapy of control group, patients in observation group were also given Shaofu Zhuyutang, 1 dose/day. A course of treatment was 3 menstrual cycles. Before and after treatment, cox menstrual symptom scale (CMSS) of COX, visual simulation of dysmenorrheal (VAS), chronic pelvic pain, pictorial blood loss assessment chart (PBAC) and cold coagulation and blood stasis syndrome were scored. And uterine volume and endometrial thickness were evaluated by B-mode ultrasonography. And levels of VEGF, MMP-9, TIMP-1, prostaglandin E2 (PGE2), prostaglandin F2α(PGF2α) and cancer antigen were detected. Result:After treatment, the clinical efficacy in observation group was superior to that in control group (Z=2.445, PPP2α and CA125 were lower than those in control group (P2 were higher than those in control group (PConclusion:In addition to desogestrel and ethinylestradiol tablets combined with Zheng's Rebuzhen therapy, modified Shaofu Zhuyutang can relieve pain and hemorrhage and improve the clinical efficacy. The mechanism may be correlated with the regulation of expression levels of VEGF, MMP-9, TIMP-1 and prostaglandin.