CT manifestations of the thymic carcinoid and literature review / 南方医科大学学报

<p><b>OBJECTIVE</b>To investigate the CT manifestations of thymic carcinoid and assess the diagnostic value of CT for this disease.</p><p><b>METHODS</b>CT and clinical findings of 5 patients (4 males and 1 female, average age 41 years) with histologically confirmed thymic carcinoid were retrospectively analyzed.</p><p><b>RESULTS</b>The clinical findings of the 5 patients showed no specificity, and none of the patients presented with carcinoid syndrome. The tumors were relatively large (mean size on the largest planar of 11.7 cm x 7.6 cm) with heterogeneous density, and showed necrosis or cystic degeneration in the tumor. The lesions showed uneven enhancement in contrast-enhanced imaging and displayed linear enhancement of the blood vessels in the tumors in 3 cases with unclear tumor margins. The adjacent major vessels were displayed in 4 cases (the superior vena cava in 2 and brachiocephalic vein in 4 cases), and 5 showed mediastinal and/or root of the neck lymphatic metastasis. None of the cases have lung or other site metastasis.</p><p><b>CONCLUSION</b>The CT findings of the thymic carcinoid have some characteristics, and can be helpful in the diagnosis.</p>

Correlation between magnetic resonance imaging findings and proliferating cell nuclear antigen expression in peripheral lung cancer / 南方医科大学学报

<p><b>OBJECTIVE</b>To study the correlation between magnetic resonance imaging (MRI) findings and proliferating cell nuclear antigen (PCNA) expression in peripheral lung cancer.</p><p><b>METHODS</b>The expression of PCNA was detected by means of SABC immunohistochemistry in 45 cases of surgically and pathologically confirmed peripheral lung cancer. The correlation between PCNA expression in the tumors and the MRI findings was analyzed.</p><p><b>RESULTS</b>PCNA expression was correlated to the differentiation, tumor size, lobulation, and mediastinal lymph node metastasis of the tumors (P<0.05), but not to the histological type, clinical stage, pleural retraction, spiculation, or signal feature.</p><p><b>CONCLUSION</b>Correlations are found between MRI findings of lung cancer and abnormal expression of PCNA.</p>