Effective evaluation of presurgical nasoalveolar molding devices in the treatment of complete unilateral cleft lip and palate patients / 华西口腔医学杂志

<p><b>OBJECTIVE</b>To evaluate the orthopedic effect of presurgical nasoalveolar molding (PNAM) devices on the palatal deformities in unilateral complete cleft lip and palate (UCCLP) patients.</p><p><b>METHODS</b>Three groups with 19 patients each were studied. All samples in groups A and B were non-syndromic UCCLP children. Group A was treated with PNAM prior to operation. Group B was untreated prior to operation. Samples in group C were normally developed nose and lip palate infants aged three months. The orthotopic palate photos before and after PNAM treatment for group A, as well as pre-operative photos of groups B and group C, were taken and measured. All statistics were analyzed using SPSS 21.0.</p><p><b>RESULTS</b>PNAM treatment significantly increased the AW, AC, and PA of UCCLP patients (P < 0.05), whereas CPW, CWA, CWAS, CWAH, PMD, and CA significantly decreased (P < 0.05). However, no significant difference was observed with the cases in group C (P < 0.05). The AW, CPW, CA, and PA of the patients in group B significantly increased compared with the cases in group A before PNAM treatment (P < 0.05). Multivariate analysis of variance indicated that TW had no statistically significant difference among the three groups (P > 0.05).</p><p><b>CONCLUSION</b>PNAM treatment is a non-surgical early treatment for the effective improvement of palatal primary deformities in UCCLP patients.</p>

The Efficacy of Intravenous Azithromycin for Treatment of Bacterial Infectious Diseases / 医药导报

Objective: To observe the efficacy of azithromycin in treating the bacterial infectious diseases.　Methods: Intravenous administration of azithromycin was carried out in 40 cases.　Results: The clinical cure rate and eradication rate were 85.0% and 84.8%, respectively. Drug sensitivity tests showed that more isolates were sensitive to azithromycin (87.9%) than to erythromycin (42.4%). The MIC of azithromycin was lower than that of erythromycin. In addition, the adverse effects occurred with low frequency and were usually mild.　Conclusion: Azithromycin is effective and safe in treating bacterial infectious diseases.