ABSTRACT
AIM:To analyze the efficacy of modified pterygium resection combined with conjunctival autograft transplantation(CAT)in the treatment of pterygium.METHODS: A total of 140 patients(154 eyes)with pterygium treated in the ophthalmology department of our hospital from January 2018 to January 2021 were selected and grouped according to random number table method. In the observation group, 70 cases(76 eyes)were treated with modified pterygium excision combined with CAT, and improved iris restorer was used during the operation. In the control group, 70 patients(78 eyes)were treated with conventional pterygium excision combined with CAT, during which traditional iris restorer was used. Follow up for 1a, the postoperative vision, subjective symptoms, conjunctival signs(conjunctival congestion and chemosis), corneal epithelial healing, postoperative complications and recurrence rate were compared between the two groups.RESULTS: Compared with pre-operation, vision of the two groups decreased significantly on 1, 3 and 5d after operation(P<0.05), while there was no statistically significant difference between the groups(P>0.05). Compared with 1d after operation, the scores on subjective symptoms, conjunctival hyperemia and edema in the two groups decreased significantly on 3, 5 and 14d after operation(P<0.05), and those scores of the observation group on 3, 5 and 14d after operation were significantly lower than those of control group(P<0.05).The corneal fluorescein staining(FL)scores of the observation group on 3, 5 and 14d after operation were significantly lower than those of the control group(P<0.05). The proportion of repair time of corneal epithelial defect ≤5d in the observation group was significantly higher than that in the control group(P<0.05). The incidence rates of conjunctival granuloma, symblepharon, and the recurrence rate in the observation group were significantly lower than those in the control group(P<0.05).CONCLUSION: Modified pterygium resection combined with CAT is effective in the treatment of pterygium, which can alleviate postoperative irritative symptoms, conjunctival congestion and edema, and it is more conducive to postoperative corneal epithelial reconstruction, reduction of postoperative complications and recurrence rate.
ABSTRACT
@#AIM: To explore the correlation between vitamin D(Vit-D)deficiency and age-related macular degeneration(ARMD).<p>METHODS: A total of 423 cases of middle-aged and aged outpatients(age>45 years)who participated in the physical examination in ophthalmology clinic of Yuncheng First Hospital during February 2018 to February 2019 were included in the cross-sectional study. The clinical information(including sex, age, family history of ARMD, <i>etc.</i>)and biochemical indices(including 25-hydroxyvitamin D \〖25(OH)D\〗, <i>etc.</i>)were collected. The correlations between serum 25(OH)D level and clinical information, as well as biochemical indices, were analyzed. The outpatients were divided into ARMD group(231 cases)and non-ARMD group(192 cases)according to the ARMD situation in the study. The correlation between Vit-D deficiency and ARMD was analyzed.<p>RESULTS: Serum 25(OH)D level was positively correlated with the male, duration of outdoor light exposure(<i>P</i><0.05), and negatively correlated with age, smoking and drinking(<i>P</i><0.05). Binary Logistic regression analysis showed that Vit-D deficiency was a risk factor associated with ARMD(<i>OR</i>=1.980, 95% <i>CI</i>: 1.829-2.201, <i>P</i><0.01). Other associated factors included age, sex, hypertension, diabetes, low-density lipoprotein cholesterol(LDL-C), and duration of outdoor light exposure >5h/d, which were also risk factors associated with ARMD.<p>CONCLUSION: Nutritional imbalance due to Vit-D deficiency might be associated with the occurrence of ARMD. Appropriate sun exposure or vit-D supplements could contribute to preventing the development of ARMD.