ABSTRACT
<p><b>OBJECTIVE</b>To investigate the clinical manifestation of patients with renal injury induced by chronic mercury intoxication and the application of the diagnostic criteria of occupational mercury poisoning.</p><p><b>METHODS</b>The clinical data of 8 patients with chronic occupational mercury intoxication were analysed and evaluated.</p><p><b>RESULTS</b>All the observed clinical signs of chronic mercury intoxication correspond with the items of the diagnostic criteria of occupational mercury poisoning. The increasing beta2-MG was one of the clinical manifestations of renal injury induced by chronical mercury intoxication. The renal injury obviously was dose-dependent and reversible.</p><p><b>CONCLUSIONS</b>The national diagnostic criteria of occupational mercury poisoning is practically valuable. The renal injury induced by chronic mercury intoxication should not be neglected.</p>