ABSTRACT
506 persons, over 45 years old, were observed; and 74 percent of them were found lens opacity. The proportion and degree of opacity were exacerbated with increased age. 51.6 percent of 375 persons with lens opacity had hyperlipemia while 18.3 percent of 131 persons with clear lens also had it. And hypertriglyceridemia was the major manifestation of hyperlipemia. It is suggested that hypertriglycendemia has a close relationship to cataract formation.
ABSTRACT
A large series of lens were collected from normal and senile cataractous human eyes, and were investigated according to the theories of oxyradical and lipid peroxide (LPO). The findings showed that the activities of superoxide dismutase (SOD), glutathione peroxidase (GSH-Px) and catalase in the senile cataractous lens were very significantly lower than those in the normal ones, while the content of malondialdehyde (MDA) in the lens of senile cataractous eyes was very significantly higher than that of normal eyes. The results suggest that the oxyradical and LPO might be one of the direct causes leading to senile cataract formation.