ABSTRACT
OBJECTIVE:To observe the efficacy and safety of sertraline combined with Shumian capsule for depression of dyssomnia.METHODS:86 patients with depression were randomly assigned to receive sertraline alone(single group) or in combination with Shumian capsule(combined group) for 8 weeks.Clinical effectiveness was evaluated using HAMD and PSQI,and TESS was used to assess the adverse effects.RESULTS:After treatment for 8 weeks,the total effective rate was 88.2% for combined group and 85.7% for single group(P
ABSTRACT
OBJECTIVE:To discuss the way for hospital pharmacists to inprove pharmaceutical care by means of psychologic pharmacodynamics.METHODS:The literature about psychologic pharmacodynamics was reviewed and an aggregate analysis was carried out based on author's clinical practice.RESULTS & CONCLUSION:The psychologic effects in different patients during medication varied,and the psychologic effects may influence the physiological effect of drugs so as to influence the therapeutic effect.Hospital pharmacists should not only master the basic knowledge of medication,but also learn knowledge about general psychology and psycho-pharmacodynamics,strengthen communication with their patients,improve patient's compliance and maximize physiological effect of drugs.
ABSTRACT
OBJECTIVE:To observe the efficacy and adverse reaction of venlafaxine combined with Bailemian capsule for somatization disorder.METHODS:145 patients with somatization disorder were randomly assigned to receive venlafaxine alone (single group) or in combination with Bailemian capsule (combined group) for 8 weeks.Clinical global impression scale (CGI) and symptom check (SCL-90) were used to assess the efficacy and treatment emergent symptom scale (TESS) was used to assess the adverse reactions.RESULTS:After 8 weeks of treatment,CGI score showed the total effective rate were 88.14% for single group and 94.18% for combined group (P
ABSTRACT
AIM:To evaluate the efficacy of Bailemian Capsule(bulbus lilii,Radix et rhizome seu acanthopanacis senticosi caulis,Caulis polygoni multiflori,Flos albiziae,Concha margaritifera) in combination with buspirone in generalised anxiety disease. METHODS:Seventy-seven patients with generalized anxiety disease were randomly assigned to two groups:Bailemian Capsule in combination with buspirone in the treated group; buspirone alone in the control group. A period of six weeks was one treatment course in each group. The clinical effectiveness was evaluated according to HAMA reactions. RESULTS:HAMA score(P