ABSTRACT
Two cases in which Shakuyakukanzo-to (extract) was effective for spasms in the lower limbs. The spasms in these two cases were associated with central nervous system disorders affecting the brain or spinal cord.<br>The first case was a 61-year-old woman suffering from myelitis sequela. The spasms in her lower left leg increased in severity in the winter, and she experienced difficulty bending her left knee and walking.<br>The second case was a 29-year-old woman with convulsive cerebral anesthesia. Walking had become difficult with exacerbation of her sciatica and with increased spasms in her feet.<br>In both cases, the various muscle relaxants were not sufficiently effective. Regular administration of Shakuyakukanzo-to, however, had a remarkable immediate effect in decreasing spasms and facilitating walking.