ABSTRACT
OBJECTIVE@#To investigate the effect of nasal instillation of vitamin D3 on patients with allergic rhinitis symptoms including nasal itching, sneezing, clear nasal discharge, and nasal congestion.@*METHOD@#Thirty subjects with allergic rhinitis proved by skin prick test (SPT) and 30 subjects with deviated septum alone were recrui ted and administrated with 300 000 IU of vitamin D3 by nasal instillation weekly. Seven days after the intervention, the four major symptoms including nasal itching, sneezing, clear nasal discharge, and nasal congestion were evaluated by score.@*RESULT@#After intranasal instillation of vitamin D3, the symptoms in allergic rhinitis group in cluding nasal itching, sneezing, nasal discharge and nasal congestion, and serum 25-hydroxyvitamin D level has statistical differences (P < 0.05).@*CONCLUSION@#Vitamin D3 could be well absorbed through nasal mucosa. It demonstrated to have significantly effect on serum 25-hydroxyvitamin D to improve the symptoms for patients with allergic rhinitis. Vitamin D3 may be a kind of adjuvant therapy for prevention and treatment of allergic rhinitis.
Subject(s)
Adult , Female , Humans , Male , Middle Aged , Young Adult , Administration, Intranasal , Cholecalciferol , Rhinitis, Allergic , Drug TherapyABSTRACT
OBJECTIVE@#To explore the distribution of allergen tested by skin prick test (SPT) in about 5,843 allergic rhinitis patients in south Shanghai.@*METHOD@#SPT test was conducted in 5,843 allergic rhinitis patients who came to our clinic from January 2007 to August 2012. The result was analyzed by age, sex and year.@*RESULT@#The top three allergens by percentage are dermatophagoides pteronyssinus, dermatophagoides culinae and fungus among 15 common allergens. Incidence rate between male and female in each year had statistical significance, both of which showed no increasing trend with year. Incidence rates among different age groups aging from 6 to 17 years' old had no statistically significant difference, but statistically significant difference among different age groups existed in other age groups. Incidence rate showed increasing trend with year in age group of 40-65, which was not observed in other groups. The incidence rate showed decreasing trend with age in male and female, while the incidence rate in male was always higher than female.@*CONCLUSION@#In south Shanghai, primary allergens causing allergic rhinitis are dermatophagoides pteronyssinus, dermatophagoides culinae and fungus. Statistically significant difference about allergic rhinitis existed in age and sex. SPT has important significance in diagnosis of allergens.
Subject(s)
Adolescent , Adult , Aged , Aged, 80 and over , Child , Child, Preschool , Female , Humans , Male , Middle Aged , Young Adult , Allergens , Allergy and Immunology , China , Epidemiology , Rhinitis, Allergic , Diagnosis , Epidemiology , Allergy and Immunology , Skin TestsABSTRACT
OBJECTIVE@#To evaluate the impact of nasal obstruction on OSAHS.@*METHOD@#One hundred and twenty cases of OSAHS with or without nasal obstruction were analyzed by Hypno PTT(PTT)and Mallampati score (MS); Acoustic rhinometry was measured in all 120 cases.@*RESULT@#A significant correlation was found between the MS and the AHI measured during the sleep (r = 0.266, P < 0.01). The relative risk of OSAHS with a MS of III or IV in the whole group was 1.96, and 2.46 in cases with nasal obstruction.@*CONCLUSION@#A high MS represents a predisposing factor for OSAHS, especially in which associated with nasal obstruction.
Subject(s)
Humans , Nasal Obstruction , Diagnosis , Pathology , Rhinometry, Acoustic , Sleep Apnea, Obstructive , Diagnosis , Pathology , Tongue , PathologyABSTRACT
OBJECTIVE@#To discuss the method and efficacy of Wormald technique application in opening frontal recess surgery.@*METHOD@#Twenty cases with chronic frontal sinusitis underwent surgery with Wormald technique were subjected to this study. Preoperative CT scan and especially sagittal reconstructing were used to indicate the extent of lesion, source and key adjacent structure.@*RESULT@#All patients were followed up for more than half a year with an average of nine months. The effective rate was 90% and no recurrence appeared except for two cases.@*CONCLUSION@#Application of Wormald technique for frontal recess open surgery under endoscope is safe and feasible, with no intracranial, orbital, and other serious complications. All treatments including preoperative sagittal CT, that help to a clear locating the cell lead to the frontal recess obstructive lesions, awarding of the potential difficulties while frontal recess could not be identified, protecting mucous membrane in operation, and strengthening medication, washing, and oxygen spray after operation, can improve operational efficiency.
Subject(s)
Female , Humans , Male , Middle Aged , Axilla , General Surgery , Chronic Disease , Endoscopy , Frontal Sinus , General Surgery , Frontal Sinusitis , General Surgery , Treatment OutcomeABSTRACT
OBJECTIVE@#To explore the significance of the lacrimal bone at the lateral nasal wall in endoscopic dacryocystorhinostomy.@*METHOD@#The position, dimension and thickness of the exposed lacrimal bone at the lateral nasal wall in 10 cadaveric heads(male 5, female 5) were examined and the anatomy of uncinate process, the maxillary line and M point were studied, too.@*RESULT@#The lacrimal bone at the lateral nasal wall is always situated immediately anterior to the uncinate process. The average length and width of the lacrimal bone was 9.23 mm and 3.63 mm, respectively. The lacrimal bone was very thin with an average thickness of 0.06 mm.@*CONCLUSION@#The study indicates that the lacrimal bone is so thin that a bony rongeur is usually sufficient to nibble it away. The medial wall of the sac is then removed without the use of drill or chisel with less operative trauma. The uncinate process, the maxillary line and M point are reliable landmarks in endoscopic dacryocystorhinostomy.