ABSTRACT
<p><b>OBJECTIVE</b>To evaluate the effect of furcal perforation treated with iRoot BP.</p><p><b>METHODS</b>Forty newly extracted human maxillary and mandibular molars were collected. Holes in diameter of 2 mm were prepared at the roof of the central pulp cavity of 36 samples with high speed round ball diamond in order to make perforated model, and then equally and randomly divided them into two groups. The other intact four samples were used as the negative controls. In the experimental groups, group A were repaired by iRoot BP, group B were repaired by mineral trioxide aggregate(MTA). Three samples in each group were observed under scanning electron microscope(SEM), and microleakage of others was tested by measuring the concentration of leaked glucose with the enzymatic glucose oxidase-peroxidase (GOD-POD) method.</p><p><b>RESULTS</b>Microleakage of group B was higher than group A and had statistical difference (P<0.05). The dentin and iRoot BP contacted more closely in group A, some gaps existed between the dentin and MTA in group B.</p><p><b>CONCLUSION</b>For repairing furcal perforation, the effect of iRoot BP is better than that of MTA.</p>