ABSTRACT
<p><b>OBJECTIVE</b>To observe the effects on post-stroke depression treated with acupuncture at the acu points based on ziwuliuzhu (the midnight-noon ebb-flow theory).</p><p><b>METHODS</b>Ninety-three patients were randomized into a comprehensive group, a ziwuliuzhu group and a prozac group, 31 cases in each group. In the ziwuliuzhu group, acupuncture was applied to the acupoints based on ziwuliuzhu, once a day, 5 times in a week. In the prozac group, fluoxertine hydrochloride (prozac) was prescribed for oral administration, once a day, 20 mg each time. In the comprehensive group, acupuncture based on ziwuliuzhu combined with the oral administration of prozac were adopted and the treatment frequency was the same as the ziwuliuzhu group and the prozac group. The 4-week treatment was taken as one session in the three groups and 6 sessions were required totally. The clinical efficacy and the Hamilton depression rating scale (HAMD) score and the adverse reaction were compared among the 3 groups.</p><p><b>RESULTS</b>The total effective rate was 96.8% (30/31) in the comprehensive group, better than 83.9% (26/31) in the ziwuliuzhu group and 80. 6% (25/31) in the prozac group (both P<0.05). In 4, 12 and 24 weeks of treatment, HAMD score was lower significantly than that before the treatment in the three groups (all P<0.05), and the score in the comprehensive group at each time point after treatment was lower than the other two groups (all P<0.05). In 4 and 12 weeks of treatment, there were not different significantly between the ziwuliuzhu group and the prozac group (both P>0.05). In 24 weeks of treatment, HAMD score in the ziwuliuzhu group was lower than that in the prozac group (P<0.05). For the adverse reaction, there were 2 cases in the comprehensive group, 6 cases in the prozac group and 0 case in the ziwzuliuzhu group.</p><p><b>CONCLUSION</b>The comprehensive therapy of acupuncture at the acupoints based on ziwuliuzhu and oral administration of prozac is superior to either the simple oral administration of prozac or the ziwuliuzhu acu-puncture in terms of clinical efficacy and the improvements in depressive state. Regarding the clinical efficacy, the impact of simple ziwuliuzhu acupuncture is not different significantly as compared with the simple oral administration of prozac, but it is better than the simple oral administration of prozac in terms of the long-term HAMD score and safety.</p>
Subject(s)
Aged , Aged, 80 and over , Female , Humans , Male , Middle Aged , Acupuncture Points , Acupuncture Therapy , Depression , Therapeutics , Stroke , Treatment OutcomeABSTRACT
Objective To observe the clinical efficacy of electroacupuncture at different frequencies in treating post-stroke depression. Methods A hundred patients with post-stroke depression were randomized into treatment group 1, treatment group 2, treatment group 3, and a control group, 25 in each group. The treatment groups were intervened by electroacupuncture, while 2 Hz was adopted in treatment group 1, 50 Hz in treatment group 2, and 100 Hz in treatment group 3. The control group was intervened by oral administration of Sertraline Hydrochloride tablets. The Function Independent Measure (FIM) and Hamilton Depression (HAMD) scale were adopted for observation before and after intervention, and the clinical efficacies were compared. Results The FIM and HAMD scores were significantly changed after intervention in the four groups (P<0.05). After treatment, the FIM and HAMD scores in treatment group 1 were significantly different from that in treatment group 2 and 3 (P<0.05). The FIM score in treatment group 1 was significantly different from that in the control group (P<0.05). The total effective rate was 96.0%in treatment group 1, versus 92.0%in treatment group 2, 82.0%in treatment group 3, and 84.0%in the control group. The total effective rate in treatment group 1 was significantly different from that in the control group (P<0.05). Conclusions Electroacupuncture at 2 Hz, 50 Hz, and 100 Hz all can improve the activities of daily living and depression degree in patients with post-stroke depression, while 2 Hz ranks the top in comparing the therapeutic efficacy.
ABSTRACT
Objective:To study the effect of midnight-noon ebb-flow acupoint selection on rheumatoid arthritis. Methods:120 cases of patients with rheumatoid arthritis were randomly divided into three groups:midnight-noon ebb-flow acupoint selection group,acupuncture by differentiation of symptoms and signs group,integrative group of midnight-noon ebb-flow acupoint selection and acupuncture by differentiation of symptoms and signs group. Results:In the midday-midnight flowing of qi-blood acupuncture group of 40 cases,11 cases were improved obviously,11cases were improved,9cases were improved slightly,9 cases were ineffective,the total effective rate was 77.5%. In the acupuncture by differentiation of symptoms and signs group of 40 patients,10 cases were improved significantly,11 cases were improved,11 cases were improved moderate,8 cases were ineffective,the total effective rate was 80.0%. In integrated group of midnight-noon ebb-flow acupoint selection and acupuncture by differentiation of symptoms and signs group of 40 patients,15 cases were improved significantly,13 cases were improved,10 cases were improved moderate,2 cases were ineffective,the total effective rate was 95.0%. Curative effect of the integrative group was better than that of other two groups(P