ABSTRACT
Objective To explore the relationship between serum leptin levels and insulin levels in type 2 diabetes.Methods Serum leptin concentrations were measeured by radioimmunoassay,body mass index(MBI),mean arterial blood pressure(MBP),waist to hip ratio(WHR),fasting plasma glucose(FPG),fasting serum insulin(FINS),total cholesterol(Tch),triglycerides(TG),LDL-C,HDL-C,HbA1c levels were determined in 20 obese diabetic patients(BMI≥25kg/m 2) and 20 non-obese diabetic patients with BMI0 05).⑵No matter what,in diabetic groups or in non-diabetic groups the serum leptin levels were higher in obese subjects than in non-obese individuals(P
ABSTRACT
Objective To explore the relationship between children obesity and adiponectin(ADPN),leptin(LP),and high-sensitive C-reactive protein(hsCRP).Methods Seventy-one obese volunteers as obesity group and 30 normal volunteers who matched obese volunteers in age and sex as control group were selected from 13 702 children and adolescents of 2 to 18 years old in Xiangtan city by sampling survey.The body mass index(BMI),ADPN,LP,hsCRP,fasting blood-glucose(FBG),and fasting pure insulin(INS) were checked respectively.The homeostasis model assessment for insulin resistance(HOMA-IR) and the quantitative insulin-sensitivity check index(QUICKI) were calculated.The difference between the two groups was compared and the relationship of all indexes was analyzed.Results The values of ADPN and QUICKI in obesity group were significantly lower than those of control group(P