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1.
Chinese Journal of Endemiology ; (12): 378-381, 2017.
Article in Chinese | WPRIM | ID: wpr-614421

ABSTRACT

Objective To provide data evidence for early diagnosis of bone and joint damage derived from brucellosis by analyzing its clinical and imaging characteristics.Methods Patients with brucellosis accepted in Ji'nan Infectious Disease Hospital form December 2013 to December 2014 were selected.Patients with bone and joint damage confirmed through imaging were further studied,their epidemiological and clinical characters,CT and MRI characteristics,treatment and outcome were summarized.Results Total of 97.8% (45/46) patients had a clear contact history,most of them worked in poultry farming,taking up to 67.4% (31/46).July to October was its peak time for attacking,taking up to 58.7% (27/46).The clinical manifestations of patients were joint pain,swelling and activities obstacles.In the CT images,there was obvious bony destruction,characterized by multiple round or large areas of low density insect damage sample spots.There was osteosclerotic bone lesions or osteophyte formatted in edge.The paravertebral soft tissue was swelling,and the vertebral body deformation was not obvious,and there was vertebra small joint damage occasionally.In the MRI images,there was vertebral ligaments damage,or soft tissue damage,or osteoproliferation at the edge of the vertebral bodies.There was abnormal signal T1W1 or T2W1 signal,and FS-T1W1 showed high signal,while FS-T2W1 showed slightly high signal.The diagnosis rate of CT,MRI and CT combined MRI for bone and joint damage derived from brucellosis was 76.1% (35/46),84.8% (39/46) and 91.3% (42/46),respectively.The main therapeutic drugs were doxycycline and rifampicin,and the clinical effective rate was 91.3% (42/46).Conclusion The epidemiological characters,CT and MRI characteristics of bone and joint damage derived from brucellosis have certain representativeness,and the comprehensive investigation is beneficial for clinical diagnosis.

2.
Journal of Chinese Physician ; (12): 40-41, 2016.
Article in Chinese | WPRIM | ID: wpr-493678

ABSTRACT

Objective To explore clinical manifestation and laboratory examination of brucellosis change characteristics.Methods Selection in January 2014 to December 2014 admitted during the period of 100 cases patients with brucellosis as the research object,with the method of retrospective analysis to an-alyze the data of all patients were analyzed and summarized,and on this basis,summarizes the characteris-tics of these changes.Results The incidence of brucellosis in the countryside and unexplained transmis-sion rates rise more apparent,clinical irregular fever,adopt the way of combination treatment,the effect was relatively good.Conclusions The clinical manifestations of brucellosis is relative to the diversity of the attending physician to strengthen the understanding of the disease,is the key to reduce the incidence of mis-diagnosis,adhere to the specification of antimicrobial therapy is the basic requirement of treatment.

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