Relationship between triglyceride and cholesterol levels and periodontal status

Recently some evidence has been presented that periodontal disease is associated with an increased risk of cardiovascular disease. The hypothesis of this study is that periodontitis may be associated with elevated blood lipid levels, a known risk factor for atherosclerotic disease. The levels of plasma lipids was measured in 40 subjects with chronic periodontitis [CP] and compared with those obtained in 40 controls. Periodontal variables included: Plaque Index [PLI], Probing Pocket Depth [PPD], Clinical Attachment Level [CAL] and Bleeding On Probing [BOP]. Laboratory tests included: total cholestrol, triglyceride, LDL and HDL. Statistical tests used were Kolmogorov -Smirnov, Kruskal Wallis, Spearman's rank correlation, Exact fisher and Independent Samples Student t-test. The level of statistical significance was established at P

[ comparison of fasting blood sugar of non-diabetic patients with chronic periodontitis and non-diabetics without periodontal disease]

Background: there are several systemic disorders which have adverse effects on periodontal tissue, such as diabetes. Previous studies of non-diabetic patients have demonstrated higher levels of fasting blood sugar [FBS] among those with periodontitis compared to those without periodontitis. In an attempt to clarify whether periodontal diseases incline the patients to a pre-diabetic state or not, we studied the FBS level of non-diabetics with periodontitis and compared the results with those who had no periodontal involvement

Materials and methods: eighty non-diabetics who referred to the outpatient clinics of dentistry faculty, Azad University, Tehran, during 2003 were evaluated in this case control study. 40 patients with periodontitis constituted the cases, and 40 without any periodontal disease made up the control group. Plaque index, bleeding on probing [BOP], probing pocket depth and clinical attachment loss were measured and recorded. FBS was determined for both groups and its levels higher than 126 indicated diabetes, while levels between 110 and 126 were considered as pre-diabetic state. Both descriptive and analytic analyses were applied. P-value of less than 0.05 was considered statistically significant

Results: spearman correlation test results indicate a direct relation between FBS and BOP in the control group [r = 0.382, p = 0.015]

Conclusions: our results are in agreement with previous studies in demonstrating the increase in blood glucose levels associated with periodontal tissue inflammation in the chronic periodontitis patients