[Purification and structured termination of compounds in chloroform extract of the aerial parts of the plant Ferula hirtella]

Ferula is a genus of about 130 species of flowering plants in the family Umbelliferae, of which 30 species are found in Iran. Many species of this family possess medicinal qualities and have long been used in traditional medicine. This research aims to isolate, separate and determine the structure of the compounds found in the chloroform extract of the aerial parts of Ferula hirtella. We collect F. hirtella from the site of its natural habitat in Abade, Fars Province. The chloroform extract of the aerial parts is derived and then mixture separation using Column chromatography is performed. Using Column chromatography purification methods, we were able to separate, for the first time, two coumarins, Farneciferol C and Umbelliprenin, and a steroid compound, beta-stigmasterol from the chloroform extract of the F. hirtella which were identified using C NMR and H NMR spectral data. A majority of the compounds found in the chloroform extract of the aerial parts of F. hirtella are coumarins. Separation of beta-stigmasterol from the chloroform extract of this genus was achieved for the first time

[Isolation beta-stigmasterol from teucrium hyrcanicum L., growing wild in gilan province]

The genus Teucrium [Lamiaceae] is comprised 340 species in widespread over the world. Remarkably, In the Flora Iranica this genus is represented by twelve species, three of which are endemic. The genus Teucrium are known for medicinal value, antibacterial, antioxidant, anti-inflamatory, antiseptic and antipyretic properties. Isolation of beta-Stigmasterol from Teucrium hyrcanicum L. The aerial parts of Teucrium hyrcanicum were collected during the flowering stage from Rostamabad, Gilan Province, in July 2006 and then were extracted by chloroform and acetone [2:1] for 36 h. Crude extract was separated by adsorption chromatography over silica gel with elution by petroleum and ethylacetate. Final purification was performed by smaller chromatography. A steroid named beta - Stigmasterol were isolated and the structur of them were proved using spectral data consist of FTIR, UV, HRMS, also 1-DNMR, HNMR, [13]CNMR], 2-DNMR [HMQC, HMBC] and DEPT [90[degree symbol],135[degree symbol]. beta-Stigmasterol was characterized for the first time in Teucrium hyrcanicum

[Chemical composition and antibacterial activity of the essential oil of salvia macrochlamys boiss. and kotschy, from West Azarbayjan Province]

In the Flora Iranica this genus is represented by fifthy-eight species, seventheen of which are endemic. The genus Salvia are known for medicinal value, antibacterial and antioxidant properties. Investigation on essential oil of Salvia macrochlamys and antibacterial activity assessment. The aerial parts of S. macrochlamys were collected during the flowering stage from Marmishuo Hill in West-Azarbayjan Province, in July 2006 and were hydrodistilled for 3 hours, using a Clevenger-type apparatus to yield 0.35% [w/w] of yellowish oil and analyzed with GC and GC/MS. The constituents of the essential oil were identified by comparison of their mass spectra and retention indices [RI] with those given in the literature and authentic samples. Antibacterial activities of the essential oil were investigated according to the disc diffusion method and MIC value. Thirty-four compounds were characterized in the essential oil of S. macrochlamys, representing 97.6% of the oil, of which beta-Caryophyllene [32.7%], 1, 8-Cineol [18.9%], were found to be the major components. The oil of S. macrochlamys showed high antibacterial activity against Bacillus subtilis, Staphylococcus aureus and Staphylococcus epidermidis. The oil of S. macrochlamys consists of monoterpen [44.4%] and sequiterpens [52.0%]. The antibacterial avtivity can be attributed to 1, 8-Cineol

[Chemical composition of the essential oils of two populations Teucrium hyrcanicum L. in two different localities]

The genus Teucrium [Lamiaceae] is comprised of about 340 species widespread over the world. In the Flora Iranica, this genus is represented by 12 species, of which 3 are endemic. Several Teucrium species are used in Iranian folk medicine as medicinal plant. There is no study on the volatile oil of Teucrium hyrcanicum in the literature. Investigation and comparison on essential oil constituents of two populations T. hyrcanicum collected from two localities. The aerial parts of T. hyrcanicum were collected from road of Khalkhal-Asalem and Rostamabad; shade dried and then essential oil extracted by means of hydrodistillation and analyzed with GC and GC/MS. The essential oil yields were 0.25 and 0.20 [w/w] based on dry weight of plant, respectively. 38 and 15 compounds were idedtified, representing 93.1% and 93.3% of the total oils, respectively. In the oil obtained from Khalkhal-Asalem. Hexahydrofarnesyl acetone [12.7%], linalool [11.7%] and E-beta-farnesene [10.7%] were found as the major components. From Rostamabad sample E- beta-Farnesene [60.6%] and E-beta-Farnesene [15.0%] were the most abundant. The results showed that the difference in the volatile constituents could be considered as chemotaxonomic significance and it may be attributed to their different ecological and geographical origin factors

Vanishing of a congenital intracranial aneurysm

Intracranial aneurysms in neonatal period and early infancy may be resorbed spontaneously or due to removal of predisposing factors. Herein, we presented a rare case of vanishing of a large thrombosed intracranial aneurysm in a 25-day-old girl presented with head enlargement and vomiting. Magnetic resonance imaging [MRI] revealed a severe hydrocephalus accompanied by a 1.5-cm aneurysm at the bifurcation of the right middle cerebral artery [MCA]. Doppler ultrasonography confirmed a flow with a magnitude almost similar to that of the right MCA flow, inside the mass located adjacent to it. The hydrocephalus was managed by ventriculo-peritoneal [VP] shunt. The patient underwent a conservative observation for several months. Subsequently, the aneurysm was vanished in control images