[ effects of different doses of atorvastatin on angiogenesis of chorioallantoic membrane of chick embryo]

Statins promote the proliferation, migration and survival of endothelial cells and bone marrow -derived endothelial progenitor cells [Angioblasts]. Angiogenesis, the formation of new blood vessels, is a dynamic and complex activity which is needed for embryogenesis and other physiological processes. However, in many pathological conditions such as solid tumor progression, the disease appears to be associated with persistent upregulated angiogenesis. In this research we used atorvastatin [0.1microm] and [10 microm] on angiogenesis of chick embryo. In this experimental study 42 Ross fertilized eggs were randomly divided into 3groups as follows: 1] control group, 2] group treated with atorvastatin [0.1microm], 3] group treated with atorvastatin [10microm]. In day 2 a window was opened on eggs in sterile condition and In day 8 gelatin sponge was placed on chorioallantic membrane [CAM] and was soaked with 10 microliters atorvastatin [0.1microm] and [10 microm] in group 2 and group 3. In day12 CAMs were examined and photographed by research photo-stereomicroscope in all cases. Data were analyzed statistically by ANOVA and Tukey tests. The average number and length of vessels in control and the group treated with atorvastatin [0.1microm] showed a significant increase [P<0.05] and the average number and length of vessels in the group treated with atorvastatin [10 microm] showed a significant decrease compare to control group [P<0.05]. The results of this study showed that atorvastatin has a stimulatory effect on angiogenesis in CAM and atorvastatin [10 microm] has an inhibitory effect on angiogenesis in CAM. It is suggested that astatine can be used as a new medicine for angiogenesis balancing in treat ment of diseases related to angiogenesis

[Determination of aerosol emission and bag filter efficiency in fire-proof products industries]

Today, the environmental pollution caused by fire-proof break producing factories is one of the critical and challenging issues in our country. Aerosols emission concentration of the factory stacks and determining of bag filters efficiency were aims of this study. In this research, the concentration of emitting dust from 6 stacks related to Kaolin preparation, Calcinatory, Shamout, Specific mass, Extrude Furnace and Shuttle Furnace units were measured during 2006-2008. Also, the efficiency of bag filters of Kaolin preparation, Calcinatory, Shamout, Specific mass units were determined in 2008. Devices M9096 Particulate Sampling Train and DURAG model [D-RC 80] were used in this research. The rates of dust concentrations in years 2006-9 in Kaolin unit were; 284, 112 and 12.5 mg/m3, in Shamout unit were; 120, 140 and 73 mg/m3, in Calcinatory were; 178, 179 and 173 mg/m3, Specific Mass were; 291, 283 and 60 mg/m3, in Shuttle Furnace were; 14.7, 14.3 and 14.8 and in Extrude Furnace were; 12.6, 13.7 and 12.7 mg/ m[3]. Efficiency of bag filters was 99.896% for Kaolin unit, 06.499% for Shamout unit, 92.348% for Calcinatory and 99.782% for Specific Mass unit. During 2006 and 2007 the rate of dust emission in Kaolin preparation, Calcinatory and specific mass have exceeded than the national emission standard but in 2008, the rate of dust emission from Kaolin Preparation and Specific Mass units were extensively reduced to the lower than national emission standard limit due to proper maintenance and replacing of damaged parts in time. Efficiency of bag filters has been ideal in Kaolin unit and Specific Mass unit but it was low in Shamout and Calcinatory units