Preoperative subconjunctival injection of mitomycin C versus intraoperative topical application as an adjunctive treatment for surgical removal of primary pterygium

To compare the efficacy of preoperative local injection of mitomycin C [MMC] to intraoperative application of MMC in the prevention of pterygium recurrence after surgical removal. Seventy eyes of 70 patients with primary pterygia were randomly allocated to two groups. The first group [Group A, 35 eyes] received 0.1 ml of 0.15 mg/ml of subconjunctival MMC injected into the head of the pterygium 24 h before surgical excision with the bare sclera technique. The second group [Group B 35 eyes] underwent surgical removal with the bare sclera technique with intraoperative application of MMC [0.15 mg/ml] over bare sclera for 3 min. The study was performed between March 2007 and December 2008, and follow up was performed for 1 year postoperatively. Differences between frequencies in both groups were compared by the Chi-square test or Fisher exact test. Differences between means in both groups were compared by Student's t-test. P < 0.05 was considered significant. The rate of pterygium recurrence was 5.70% in Group A and 8.57% in Group B at 1 year postoperatively [P>0.05]. Postoperatively, scleral thinning occurred in one eye in each group that resolved by 5 months postoperatively. No serious postoperative complications occurred in either group. Preoperative local injection of 0.15 mg/ml MMC is as effective as intraoperative topical application of 0.15 mg/ml MMC for preventing pterygium recurrence after surgical removal

Refinement of anterior levator resection algorithm for congenital ptosis

To analyse outcome of the Levator Resection Surgery for the correction of congenital ptosis. Design: A retrospective study. Place and Duration of Study: Three hospitals at Melbourne, Australia, from January 1990 to January 2000. Subjects and It included all congenital ptosis cases repaired by anterior levator resection. Forty seven eyelids of 44 cases were included. Twenty cases were male and 24 female. Thirty one [66%] were in Primary Surgery group, while 16[34%] in Revision Surgery group. The cumulative success rate with lid position within + 1mm of the desired level was 41/47[87%]. Good outcome was achieved in 92% of cases with levator function 8mm or better compared with only 50% of cases with levator function 6-7mm. The statistical analysis done by Chi Square test did not show any statistically difference among the groups. In the congenital ptosis with levator function 8mm or better, chances of good outcome are more after levator resection