ABSTRACT
Objective@#To explore the latent categories and general demographic characteristics of short form video addiction among college students, so as to provide empirical reference for prevention and intervention of short form video addiction among college students.@*Methods@#Convenience sampling method was used to select 1 386 college students from a certain university in Anhui Province in June 2023. A questionnaire survey was conducted among college students by using the Short Video Addiction Scale. The latent profile analysis method of "individual center" was used to explore the categories of college students short form video addiction, and multiple Logistic regression was used to explore the influence of demographic variables on the latent classification of short form video addiction.@*Results@#College students with short form video addiction were divided into three latent categories:non addiction group (22.15%, n =307), low addiction group (63.28%, n =877) and high addiction group (14.57%, n =202). The results of multiple Logistic regression analysis showed that gender, major type and family location were related with short form video addiction among college students:male students (low addiction group: OR =0.47; high addiction group: OR =0.41), cultural and historical majors (low addiction group: OR =0.66), and students from cities (high addiction group: OR =0.51) were less likely to be involved in short form video addiction ( P <0.05).@*Conclusions@#There is significant group heterogeneity in short form video addiction among college students. Families, schools and society should attach importance and pay attention to the phenomenon of short form video addiction among college students, actively take targeted intervention measures to prevent and reduce the occurrence of short form video addiction symptoms among college students.
ABSTRACT
This study investigated the expression and prognostic value of SHP-2 in cervical cancer caused by human papillomavirus (HPV) infection.Forty-five specimens from patients with cervical cancer (stage Ⅰ -Ⅲ),32 specimens from patients with cervical intraepithelial neoplasia (CIN) ( Ⅰ,Ⅱ) and 20 normal cervical samples from patients with hysteromyoma were collected in Department of Pathology for comparison.The expression levels of SHP-2 and IFN-β proteins were detected by using immunohistochemistry.The mRNA expression level of SHP-2 was detected by using quantitative real-time polymerase chain reaction (PCR).HPVs were detected by HPV GenoArray Test.The Spearman correlation was used to compare the expression level of SHP-2 in HPV infected cervical cancer vs non-HPV infected normal cervix.The level of SHP-2 protein expression in the cancer tissues (88.8％) was significantly higher than in CIN tissues (62.5％) and normal cervixes (45％) (P＜0.05 and P＜0.05,respectively).The SHP-2 mRNA levels in the cancer tissues were upregulated as compared with those in the normal cervixes (P＜0.05).Twenty-one (46.7％) cervical cancers,25 (78.1％) CINs and 17 (85％) normal cervixes showed IFN-β positive staining in cytoplasm.There was statistically significant difference in the expression rate of IFN-β between cervical cancer and normal cervix (x2=8.378,P＜0.05) as well as between cervical cancer and CIN (x2=7.695,P＜0.05).HPV16/18 infections could be found in normal cervixs (15％),CINs (68.7％) and cervical cancers (84.4％).There was a correlation between HPV infection and SHP-2 expression in cervical cancer (rs=0.653,P＜0.05).SHP-2 may be a useful prognostic and diagnostic indicator for HPV infected cervical cancer.In cervical canccrs,SHP-2 mRNA and protein overexpression was associated with IFN-β lower-expression.