ABSTRACT
Objective: To determine the correlation between Psoriasis Area Severity Index [PASI] and Dermatology Life Quality Index [DLQI] in patients of psoriasis
Study Design: Cross sectional study
Place and Duration of Study: Both outdoor and indoor patients of Dermatology Department, Military Hospital [MH] Rawalpindi for duration of 6 months i.e. from 6th Oct 2014 to 5th Apr 2014 were selected
Material and Methods: A total of 155 patients of chronic plaque psoriasis diagnosed clinically, ranging from 20 to 80 years of age and of either gender were included in the study. A careful history and clinical examination was done and for each case PASI and DLQI were calculated and registered in the designed proforma. Data were entered and analyzed in SPSS version-17.0. Mean and standard deviations were calculated for quantitative variables like age, PASI and DLQI. Frequencies and percentages were calculated for qualitative variables like gender. Pearson's correlation coefficient [r] [+1,-1] was calculated between mean PASI and mean DLQI. A p-value <0.05 was considered as significant. Stratification was done for age and gender and post stratification correlation was calculated
Results: Out of 155 patients studied, 110 [70.97%] were males and 45 [29.03%] were females. Ages of the patients ranged from 20-80 years [mean age 49.5 +/- 15.6 years]. Mean PASI score was 27.92 +/- 5.83 and DLQ1 was 11.46 +/- 4.22. The value of Pearson correlation coefficient [r] was 0.1324 which showed weak correlation between PASI and DLQ1 with p-value of 0.100. Weak correlation [r=-0.3394] in age 51-80 years while very weak correlation [r=-0.0651] in age 20-50 years was noted. PASI and DLQ1 showed weak correlation in males [r=0.132] and in females [r=0.461]
Conclusion: This study concluded that there is a weak correlation between PASI and DLQI
ABSTRACT
To find spectrum of various dermatological manifestations during hepatitis "C" virus infection in local population of hyderabad. This descriptive study was conducted in medicine department of Isra University Hospital Hyderabad from January 2011 to June 2012. A total of 325 anti-HCV positive patients were enrolled. All patients were subjected to detailed history, careful clinical examination of skin by a dermatologist to diagnose skin disease. All data was analyzed using statistical package SPSS 14.0. A total of 325 HCV positive patients [61% males and 39% females] were enrolled in this study. Mean age was 43 [SD+10 years], ranging from 15 to 78 years. About 41% had one or more dermatologic manifestations. Pruritis was the leading manifestation found in 11%, lichen planus [oral and cutaneous] was next to be found in 6.7% patients and hyperpigmentation in 5.2% patients. Urticaria [acute and chronic] was next counting in 5.23%. Jaundice, alopecia and vitiligo were seen in 4.9% each. Dry skin and interferon injection site erythema were observed in 4.6% patients each. Cutaneous vasculitis was noticed in 3.6% each, while photosensitivity, psoriasis and Raynaud's phenomenon were seen in 1.8%, 2.5%, 1.5% patients respectively. Dermatological manifestations are very common in patients with chronic HCV infection and when confronted with a suspected skin lesion, patient should be screened for it. Epidemiological studies are essential to determine the real prevalence of other dermatoses during course of HCV infection