ABSTRACT
Magnesium, the second most abundant intracellular cation have several critically important roles in human body. In addition to energy production and maintenance of electrolyte balance, magnesium [Mg[++] is essential for normal neuromuscular function, excitation contraction coupling maintenance of vessel tone, blood coagulation as well as Ca[++] and K[+] transport across the plasma membrane. Case control study. Atotal of 125 subjects enrolled for this study, 88 were AMI patients having their first episode. 37 subjects were taken as control group. These patients were classified into three groups depending on the age of the subjects. To find out serum magnesium and electrolyte levels in AMI patients at presentation to Emergency Department. Hypomagnesaemia is a common clinical finding in cases of acute myocardial infarction at their presentation to the emergency department of Punjab Institute of Cardiology, Lahore. It is very critical as ventricular tachyarrythmias cardiac arrest, sudden cardiac death, re-infarction are the usual outcome. There is Hypomagnessemia [P<0.001] in all the subgroups while for Na[+] and K[+] [P>0.05]. Our result explains the contribution of hypomagnesaemia as a minor risk factor for AMI. Therefore it is suggested that serum magnesium should be estimated in each case of AMI patient. Importance may be given to Mg[++] supplementation where needed. The dosage should not be empirical but be based on individual patient requirement