effect of heat-killed candida albicans and dentin powder on the antibacterial activity of chlorhexidine solution

The purpose of this study was to compare the inhibitory effect of heat-killed Candida albicans and dentin powder on the antibacterial activity of chlorhexidine [CHX] against Enterococcus faecalis and Streptococcus sanguis. The antibacterial effect of each group was determined by measuring the zone of inhibition diameter in millimeters after incubation at 37°C for 24 hours in a humid atmosphere. Each test was repeated three times. Data were analyzed using ANOVA and Tukey's test. Results indicated that both heat-killed C. albicans and dentin powder decreased the antibacterial activity of CHX against both tested bacteria significantly [P<0.05]. In conclusion, both heat-killed Candida albicans and dentin powder reduced the antibacterial activity of CHX significantly

[Comparison the effects of different root canal irrigants on the retention of quarts fiber posts cemented by resin cement]

Root canal irrigants could change the structure of root dentin and affect the posts retention the purpose of this study was to compare the effects of three different endodontic irrigants on the retention of quarts fiber posts cemented by different resin cements. In this in-vitro study, 10 mm long post spaces were prepared in root canals of 120 premolars after endodontic therapy and cutting the crowns at the cementoenamel junction. The teeth were randomly divided into four equal groups based on the irrigants as follows: distilled water, 2% chlorhexidine, 0.25% iodine and 1% NaOCl. Quarts fiber posts were cemented by Panavia F2. Samples were stored at 370c and humidity of 100% for one week. After thermocycling, the retention of fiber posts were measured by tensile test and modes of failure were reported. Data were analyzed by One-Way ANOVA, Tukey and Fisher's exact tests. The mean and standard deviation of the posts retention were 367.08 +/- 63.07, 377.59 +/- 72.02, 363.11 +/- 68.53 and 342.89 +/- 74.94 for distilled water, chlorhexidine 2%, iodine 0.25% and sodium hypochlorite, respectively. One-way ANOVA showed that there was a significant difference among the groups [P<0.001]. The results of Tukey test showed that posts retention was significantly higher after rinsing by chlorhexidine [P<0.01]. According to the results of this study, chlorhexidine rinse had a favorable effect on retention of posts cemented by resin cement.

Effect of hydroxyapatite and bovine serum albumin on the antibacterial activity of MTA

The purpose of this study was to compare the inhibitory effect of bovine serum albumin [BSA] and hydroxyapatite [HA] on the antibacterial activity of white-colored MTA [WMTA] against Staphylococcus [S.] aureus and Streptococcus [S.] mutans after 24 and 72 hours. All materials were prepared according to the manufacturer's directions immediately before testing. The antibacterial effect of each group [WMTA, WMTA+BSA and WMTA+HA] was determined by measuring the diameter of zone of inhibition in millimeters after incubation at 37[degree sign] C for 24 and 72 hours in a humid atmosphere. Each test was repeated three times. Data were analyzed using ANOVA and Tukey's test. In the 24 hours samples as well as in 72 hours samples, the antibacterial activity of MTA+HA group was significantly greater than two other groups against S. aureus [P<0.05]. However, the antibacterial activity of MTA+HA group against S. mutans was not significantly different from the MTA group in 24 hours as well as 72 hours samples. BSA reduced the antibacterial activity of MTA against both tested bacteria in the 24 and 72 hour samples [P<0.05]. The products studied exhibited antibacterial activity. However, in both time intervals, the MTA+HA group exerted the greatest activity against S. mutans and S. aureus

update on the antibiotic-based root canal irrigation solutions

Antibiotics are a valuable addition to health practitioners for the management of bacterial infections. During endodontic treatment and when managing trauma to the teeth, antibiotics may be applied systemically or locally. Due to the potential risk of adverse effects of systemic applications, and the ineffectiveness of systemic prescribed antibiotics in necrotic or pulpless teeth and the periradicular tissues, the local application of antibiotics may be a more effective mode for delivering antibiotics to infected root canals. The purpose of this article is to review the history, rationale, and applications of antibiotics and antibiotic-containing irrigants in endodontics