ABSTRACT
Objective: To compare the efficacy of 0.05% cyclosporine eye drops with 0.1% fluromethalone eye drops on keratoconjunctivitis sicca [dry eye disease]
Study Design: Randomized controlled trial
Place and Duration of Study: Ophthalmology department of HIT Hospital Taxila, from Oct 2014 to May 2015
Material and Methods: The patients with keratoconjunctivitis sicca [KCS] were selected from outpatient and divided in two treatment groups. The dry eye disease was defined according to criteria set by International task force for dry eye disease [ITF]. The group I was treated with 0.05% cyclosporine drops while group-II was treated with 0.1% fluromethalone eye drops three times a day after informed written consent. The patients were followed up after three months and six months
Results: At the start of treatment 94 patients were placed in two treatment groups [n=47 in each group] and all the patients with KCS were graded according to severity following rules set by ITF. There were 46 patients in grade III [severe] KCS and 20 patients in grade IV [very severe] KCS. At the end of study only 24 were in grade II [moderate] KCS and 2 in grade III KCS. Of these only 5 patients in grade II and none in grade III were in treatment group I [cyclosporine]. The remaining 19 patients in grade II and 5 patients in grade III KCS belonged to group II [fluromethalone]
Conclusion: Cyclosporine eye drops are better than fluromethalone in treatment of keratoconjunctivitis sicca
ABSTRACT
This study was aimed to visualize the frequency and type of imminent terrorist events and plan a flexible medical support hierarchy capable of effectively responding to terrorist scenarios with focused, adaptive and efficient medical support doctrines. Efficient medical support system reduces mortality, raises morale and neutralizes the effects of terrorist incidents. Medical support in low intensity conflict [LIC] is necessary to be revitalized in line with modern operations requirements. After thorough literature search all available standing operating procedures [SOP], were reviewed for medical support in LIC. To be effective, the medical support system ought to be very well carved, well rehearsed, ever evolving, innovative and practical. It is ought to be flexible and futuristic to accommodate difficult challenges, yet plausible and practical enough to conform to the ground realities. Deliberate and focused endeavors at multiple tiers involving diverse organizations with singularity of aim and purpose i.e. to render sickness preventive, health promotive and disease curative facilities where ever the nation calls in line with the splendid traditions of Pakistan Armed Forces