ABSTRACT
Objective: To determine the frequency of hepatitis C virus infection in patients with type 2 diabetes mellitus and to look for the common risk factors leading to this infection in diabetics
Study Design: Descriptive cross sectional study design
Place and Duration of Study: Department of Medicine, Combined Military Hospital [CMH] Kharian, from Jan 2015 to Jun 2015
Patients and Methods: This study was conducted in the department of Medicine, Combined Military Hospital Kharian. Through a descriptive cross sectional study design, a total of 140 patients with type 2 diabetes mellitus, admitted through casualty, OPD or private clinics were selected and tested for Hepatitis C virus infection. The common risk factors leading to such infection among positive cases were also scrutinized
Results: The mean age of patients was 48.82 +/- 10.14 with 60.7 percent female gender predominating the overall sample of diabetics. Using 3rd generation ELISA method, hepatitis C virus was found in 45 [32.1 percent] of patients with 41-50 years of age group most commonly affected age group [34.7 percent] and female [57.8 percent] commonly affected gender. The distribution of risk factors leading to hepatitis C virus in diabetics are: 21 [46.7 percent] had history of surgery in the past, 13 [28.9 percent] had history of blood transfusion in the past, 7 [15.55 percent] had history of hemodialysis while only 4 [8.9 percent] had history of tattooing in the past
Conclusion: Hepatitis C virus infection is still a common problem in diabetic patients of our local population and we recommend further research work over its risk factors so that the guidelines for its control may be formulated
ABSTRACT
Objective: To determine the frequency of factors leading to metabolic syndrome among non-alcoholic fatty liver disease [NAFLD] patients at a tertiary care hospital
Study Design: Descriptive cross sectional study
Place and Duration of Study: Department of Medicine, Combined Military Hospital, Kharian. Study was carried out over a period of six months from Jan 2015 to Jun 2015
Material and Methods: A total of 110 patients were included in this study. Past history was taken to rule out alcohol intake, viral and drug induced etiology, to determine the presence of co-morbidities like obesity, type 2 diabetes mellitus, arterial hypertension and dyslipidemia. Physical examination was carried to determine the arterial blood pressure and to determine anthropometric data that is weight, height, body mass index [BMI] and abdominal obesity by measuring waist circumference
Results: Mean age of the patients was 49.95 +/- 8.86 years. There were 72 male patients [65.5%] while 38 [34.5%] patients were female. Different metabolic factors were central obesity in 82 patients [74.5%], raised high density lipoprotein [HDL] in 19 patients [17.3%], raised cholesterol in 87 patients [79.1%], raised blood pressure in 65 patients [59.1%] and raised fasting plasma glucose in 82 patients [74.5%]. Mean BMI was 26.31 kg/m2 +/- 2.68, mean waist circumference was 109.82 cm +/- 18.41, mean cholesterol was 237.50 +/- 48.47mg/dl, mean systolic blood pressure was 148.88mmHg +/- 22.10, mean diastolic blood pressure was 90.41mmHg +/- 12.25 and mean fasting plasma glucose was 113.28mg/dl +/- 22.80. Stratification with regard to age was carried out
Conclusion: A considerable number of patients with NAFLD had metabolic syndrome. There was a close correlation between NAFLD and metabolic syndrome