ABSTRACT
Living cell membranes, even in the absence of any ambient or applied electric fields, are known to have associated with them weak intrinsic noise, generated as a result of various biochemical and physiological processes taking place in and around the plasma membrane bilayer. This paper presents the theoretical backgroupd and details of a biophysical study in the measurement of intrinsic membrane electromagnetic noise within living cells in vitro, on the basis of which a spectroscopy technique is, defined. Initial studies have been carried out with cultured yeast cells [Saccharomyces cerevisiae]. A number of successful recordings of intrinsic noise from aerobic cells have been carried out, demonstrating the presence of intrinsic fields in living and aerobically-respiring cells in an electromagnetically-shielded environment. Our studies also reveal the effect of aerobioc respiration on the studied cells, whereby conspicuously higher magnitude noise spectra were seen with aerobically-respiring active yeast cells, as compared to anaerobic cells. The recorded noise had spectral region within the range of Extremely-Low-frequency [ELF] part of the spectrum