ABSTRACT
The aim of this study was to determine the effect of 9 weeks aerobic exercise and multivitamin supplement on plasma level of HCY, CRP and TNF-alpha in non-athletic obese women. Total 30 sedentary and healthy obese women aged 25-50 year and BMI >/=30 Kg/m2 volunteered for this study. The subjects were randomly categorized into three experimental groups, aerobic group, aerobic-supplement group, and a nonintervention control group. The experimental groups went through a 9-week [3 days per week] aerobic exercise program. Blood samples were taken of all subjects before and after the aerobic exercise program at overnight fast. The data were analyzed through paired t test, ANOVA, and Dant. The significance level was p<0.05. Aerobic and aerobic-supplement exercise decreased the rate of HCY [p=0.013], CRP [p=0.001] and TNF-alpha [p=0.006] in obese women significantly, also the reduction of basic rates of CRP and TNF-alpha in aerobic group [p=0.001] and aerobic-supplement group [p=0.001] were significant compared to control group. But reduction of basic HCY levels was not significant, though. This reduction was significant in aerobic-supplement group [p=0.036]. This prospective data indicate that aerobic exercise with definitive intensity and multivitamin supplement decreased cardiovascular risk factors in obese women. Therefore as a modifiable lifestyle factor should be encouraged in obese adults for prevention of cardiovascular events