ABSTRACT
Objective: To evaluate the efficacy of non-tensile tunica albuginea plication (NTTAP) using nonabsorbable sutures for the correction of congenital and acquired penile curvature and to determine the key points for a successful outcome of this procedure. Patients and Methods: From June 2004 to July 2007; 43 patients with penile curvature (35 congenital and 8 secondary to Peyronie's disease) underwent surgical correction by NTTAP. The indications were difficult or impossible vaginal penetration; and a cosmetically unacceptable penis. For tunica albuginea plication (TAP) we applied the 16 dot procedure using non-absorbable sutures (Tycronr 2/0 polyester fiber). Results: After a mean follow-up period of 18 months; successful results with respect to penile straightening; normal erection; penetration and sensation; confirmed both subjectively and objectively; were achieved in all patients. Post-operative penile shortening of less than 1.5 cm was present in 50of the cases; but did not affect intercourse. Post-operative complications were mild and reversible; they consisted of penile skin necrosis after circumcising incisions and post-operative pain upon nocturnal erection that subsided after a few weeks with the frequent use of ice compresses. The overall satisfaction rate was nearly 100(35/43 very satisfied and 8/43 satisfied). Conclusion:NTTAP is a simple and effective method for the correction of congenital and acquired penile curvature. The key points for successful appropriate expectations; and careful discussion of the location of the suture sites. There is no need for mobilization of the urethra or neurovascular bundle; which adds a great advantage to this easy and simple technique. Cutting through the tunica albuginea; which may prevent postoperative erectile dysfunction; is not necessary. A disadvantage of this procedure is that it cannot correct hour-glass deformity
Subject(s)
Penile Induration , Postoperative Complications , Urologic Surgical ProceduresABSTRACT
A total of 75 P. aeruginosa isolates were secured out of 280 samples from diseased chickens suffering from different respiratory manifestations. The isolates were characterized and serotyped. The most prevalent serotypes were O3 and O4. An inactivated bivalent P. aeruginosa vaccine was prepared from these serotypes. The inactivation was achieved through irradiation with Cobalt 60. The quality control analysis of the prepared irradiated vaccine indicated that it was safe and its use was not associated with any clinical distress. Application of ELISA for evaluation of humoral immune response developed against P. aeruginosa in the vaccinated chicken groups showed significant increase in antibody titers, which was influenced by the route of immunization. The protection rates post challenge reached 100%, 96% and 90% among the intramuscularly, subcutaneously and orally vaccinated chicken groups, respectively. Also, vaccination of egg laying hens with the prepared vaccine stimulated formation and concentration of P. aeruginosa. specific IgY in the egg yolk