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Journal of International Pharmaceutical Research ; (6): 761-767, 2016.
Article in Chinese | WPRIM | ID: wpr-498166

ABSTRACT

Objective To optimize extraction process of Yinsangju solid beverage(YSJ). Methods The extraction of YSJ was preliminarie optimized through the orthogonal design,and then further optimized by Box-Behnken design-response surface with the overall desirability(OD)of chlorogenic acid and polysaccharide content and yield of extract as evaluation indexes. Results The op?timum extraction of orthogonal design was as follow:10 times the amount of water,soaked 0.5 h,extracted 2 times,each time 1.5 h. The optimum extraction of Box-Behnken design was 10.82 times the amount of water,soaked 0.51 h,extracted 2 times,each time 1.77 h. Conclusion The test results show that the Box-Behnken response surface method optimization of extraction process parameters is more precise and more detailed and predictability is good,and the product quality is improved.

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