ABSTRACT
Objective: To evaluate the estrogen receptor [ER], progesterone receptor [PR] and HER-2 receptor expression in breast cancer patients
Design: A Retrospective Study
Setting: Oncology Department, King Hamad University Hospital, Bahrain
Method: All women with a confirmed diagnosis of breast cancer via biopsy from 2010 to 2016 were reviewed. The following were documented: age, type, and stage of cancer
Result: Eighty-nine patients were included in the study. A total of one hundred and two patients were diagnosed with breast cancer based on biopsy results; thirteen patients were excluded due to the unknown stage and/or grade. The mean age was 53.9 years. The majority of cases were infiltrating ductal carcinoma [IDC], 82 [92%]. The most common molecular subtype detected in the study was Luminal B [ER+, PR+, HER2+], 29 [32.6%] of the study population. Nine [10%] had an unknown grade, and 8 [8.9%] had unknown stage were excluded from the analysis
Conclusion: Many patients were lost to follow-up. More effort is needed to reduce the proportion of unknown stages and grades of breast cancer cases. Further research is advised to evaluate the prognosis of breast cancer patients in Bahrain due to the high incidence in the Gulf Cooperation Council [GCC]
ABSTRACT
Background: Antibiotics have changed the practice of medicine. The widespread use of antibiotics has led to the emergence of drug resistance. The Global Point Prevalence Survey of Antimicrobial Consumption and Resistance [Global-PPS] is a motivated project to develop the point-prevalence surveys [PPS] carried out by the European Surveillance of Antimicrobial Consumption [ESAC]
Objective: To monitor the prescription of antibiotics, improve the quality of antibiotics prescription and determine the variations in drug prescription. Design: A Prospective Study. Setting: Salmaniya Medical Complex, Bahrain
Method: The Laboratory of Medical Microbiology [UA, Belgium] designed the Global-PPS WebPPS program, a web-based application for data-entry and reporting. Online registration of participating hospitals on the WebPPS program was performed by the locally designated personnel. All wards in the hospital were included in the data collection. Three hundred seventy two patients were included in the study. Data collected from 1 February 2015 to 30 April 2015 were documented
Result: Three hundred seventy-two patients were included in the study. Three hundred and seven [82.5%] patients were adults, 45 [12.1%] were children and 20 [5.4%] were neonates. Two hundred sixty-three [70.7%] were on antibiotics. All the children, 45 [12.1%] were on antibiotics. beta-lactams other than penicillin was prescribed in 158 [42.5%] patients followed by penicillin in 57 [15.3%] patients. The most common indication for antibiotics use was pneumonia, 43 [11.5%] patients and lower urinary tract infections, 31 [8.3%] patients
Conclusion: The point prevalence study has shown an overuse of antimicrobials with an increasing use of drugs, particularly among pediatrics. Therefore, antibiotic supervising initiatives to limit the overuse is needed