ABSTRACT
<p><b>OBJECTIVE</b>To study the proper way of using combined postoperative chemo-radiotherapy and prognostic factors of soft tissue sarcoma.</p><p><b>METHODS</b>The clinical data of 184 patients were retrospectively reviewed. These patients were devided into surgery group (S, 94 patients), surgery plus postoperative radiotherapy group (S + R, 62 patients) and surgery plus chemotherapy group (S + C, 28 patients).</p><p><b>RESULTS</b>The 5-year survival rates of S, S + R and S + C groups were 39.4%, 48.4% and 28.6%, respectively. Combined multitherapy was the key to improve survival rate and life quality. Clinical stage, pathological type and therapeutic method were also important prognostic factors for the long term survival.</p><p><b>CONCLUSION</b>Surgery plus postoperative radiotherapy can improve the 5-year survival rate of soft tissue sarcoma.</p>