ABSTRACT
OBJECTIVE: To study the water-soluble constituents of Clerodendranthus spicatus. METHODS: Various column chromatographic techniques were used to isolate the constituents, and their structures were identified by comparing their spectral data with those in literature. RESULTS: Fifteen compounds were isolated and elucidated as caffeic acid(1), caffeic acid methyl ester(2), caffeic acid ethyl ester(3), danshensu(4), ethyl 3, 4-dihydroxyphenyllactate(5), rosmarinic acid(6), methyl rosmarinate(7), ethyl rosmarinate(8), isorinic acid(9), dihydroconiferyl alcohol(10), dihydrosinapyl alcohol(11), salvianolic acid C(12), salvian-olic acid H(13), 3′-O-(8″-Z-caffeoyl) rosmarinic acid methyl ester(14) and baicalein(15). CONCLUSION: Compounds 2, 4-5 and 9-15 are obtained from this species for the first time.