ABSTRACT
<p><b>OBJECTIVE</b>To compare the differences between advanced percutaneous vertebroplasty and routine percutaneous vertebroplasty,and evaluate the clinical application of advanced percutaneous vertebroplasty in treating senile osteoporotic vertebral compression fracture.</p><p><b>METHODS</b>From January 2010 to January 2011,28 patients with senile osteoporotic vertebral compression fracture were concealed random allocated to advanced percutaneous vertebroplasty and routine percutaneous vertebroplasty group according to whether using advanced percutaneous pedicle puncture. Of them,there were 5 males and 23 females with an average age of (70.50 +/- 9.33) years old (ranged, 53 to 85). Course of disease was from 2 to 28 days with an average of (7.62 +/- 4.52). The fracture involved 34 vertebral bodies (19 segments of thoracic vertebrae and 15 segments of lumbar vertebra), 3 day's antibiotics were applied to prevent infections. The opreation time, X-ray fluoroscopy times were compared, and pain relief effect were evaluated by VAS (visual analogue scales) score.</p><p><b>RESULTS</b>For operation time, there were significant meaning between routine group (49.00 +/- 7.74) min and advanced group (32.36 +/- 4.81) min (t = 6.828,P = 0.000 < 0.05); X-ray fluoroscopy times in advanced group (4.28 +/- 1.38) times was shorter than routine group (8.78 +/- 2.33) times, and had statistical significance (t = 6.222, P = 0.000 < 0.05); while there were no meaning in VAS scores between routine group (2.85 +/- 0.94) and advanced group (2.57 +/- 1.08) (t = 0.740, P = 0.456 > 0.05).</p><p><b>CONCLUSION</b>Compared with routine group, advanced group can shorten opreration time, reduce radiological hazard, further reduce image monitoring costs and surgical risk, and benefit from the application of advanced percutaneous vertebroplasty in treating senile osteoporotic vertebral compression fracture. Furthmore, it can provide reference to vertebral body biopsy and minimally invasive of pedicle screw fixation.</p>