ABSTRACT
Objective To systematically review the effects of exercise on systemic inflammation of chronic obstructive pulmonary disease (COPD) and skeletal muscle dysfunction. Methods The literature about the effect of exercise on COPD systemic inflammation and skeletal muscle dysfunction were retrieved from PubMed, Web of Science, CNKI, VIP and Wanfang data, until June, 2021, supplemented by reference review and manual retrieval. Results A total of 192 literatures were retrieved and eight were included, involving 245 subjects. The comprehensive results showed that exercise could decrease the level of pro-inflammatory factors and increase the level of anti-inflammatory factors. Exercise can improve the motor ability and skeletal muscle structure of patients with COPD. Exercise can improve systemic inflammation of COPD, which is related to the mode, intensity and duration of exercise. Exercise may affect ubiquitin-protease, insulin-like growth factors -1/phosphatidylinositol 3 kinase/Akt and other pathways by regulating the inflammatory response, and improve skeletal muscle dysfunction. Conclusion Exercise has certain effect on reducing systemic inflammation and improving skeletal muscle dysfunction.
ABSTRACT
Objective To systematically review the effects of exercise on systemic inflammation of chronic obstructive pulmonary disease (COPD) and skeletal muscle dysfunction. Methods The literature about the effect of exercise on COPD systemic inflammation and skeletal muscle dysfunction were retrieved from PubMed, Web of Science, CNKI, VIP and Wanfang data, until June, 2021, supplemented by reference review and manual retrieval. Results A total of 192 literatures were retrieved and eight were included, involving 245 subjects. The comprehensive results showed that exercise could decrease the level of pro-inflammatory factors and increase the level of anti-inflammatory factors. Exercise can improve the motor ability and skeletal muscle structure of patients with COPD. Exercise can improve systemic inflammation of COPD, which is related to the mode, intensity and duration of exercise. Exercise may affect ubiquitin-protease, insulin-like growth factors -1/phosphatidylinositol 3 kinase/Akt and other pathways by regulating the inflammatory response, and improve skeletal muscle dysfunction. Conclusion Exercise has certain effect on reducing systemic inflammation and improving skeletal muscle dysfunction.
ABSTRACT
Objective To study the effect of continuous nursing on the growth and development of extremely low birth weight preterm infants. Me thods 80 cases of extremely low birth weight preterm infants treated in the Dept. of Pediatrics, The Third People's Hospital of Yunnan Province from October 2015 to October 2016, were selected and divided into 2 groups: experimental group and control group, 40 cases in each group. The control group was given conventional nursing, the experimental group was given continuous nursing. Then the growth and development of infants in the two groups were compared. Re s ults The weight, body length, head circumference in the experimental group were significantly better than the control group, the difference was statistically significant (P ＜ 0.05). The readmission rate in 6 months of infants in the experimental group was lower and the parents satisfaction was significantly higher than that of control group, the difference was statistically significant (P ＜0.05). Conclus ion Conventional nursing has significant effect for extremely low birth weight preterm infants, it can improve the growth and development of infants, reduce the hospital readmission rate, and improve parents' satisfaction.