Clinical study on effect of tuihuan decoction rectoclysis in hyperbilirubinemia of newborn / 中国中西医结合杂志

<p><b>OBJECTIVE</b>To study the therapeutic effect and feasibility of rectoclysis with Tuihuang decoction (RTD) in treating hyperbilirubinemia of newborns.</p><p><b>METHODS</b>One hundred and seventy-five newborns with hyperbilirubinemia were randomly divided into the treated group and the control group. They were treated with western medicine plus double faced blue treatment while the treated group were given RTD additionally. Blood bilirubin was detected by micro-bilirubin detector daily during the treatment course. The time of jaundice regression, the speed of blood bilirubin reducing, liver function, and condition of rebounding were observed.</p><p><b>RESULTS</b>The 7-day curative rate of jaundice in the treated group was superior to that in the control group, showing significant difference (P < 0.05). The average speed of blood bilirubin reducing daily in the treated group was quicker than that in the control group (P < 0.01). The improvement of liver function, such as AST, ALT and gamma-GT in the treated group was superior to that in the control group (P < 0.01). Rebound rate of blood bilirubin in the control group was significantly higher than that in the treated group (P < 0.05).</p><p><b>CONCLUSION</b>RTD is an ideal therapy for treatment of hyperbilirubinemia of newborn, it shows obvious clinical efficacy and can effectively prevent the rebound of blood bilirubin.</p>

Clinical study on integrative Chinese and Western medicine in treating allergic purpura and preventing renal impairment / 中国中西医结合杂志

<p><b>OBJECTIVE</b>To observe the clinical effect in treatment of the recurrent allergic (Henoch-Schönlein) purpura and prevention of renal impairment by means of integrative Chinese and Western medicine (ICWM).</p><p><b>METHODS</b>One hundred and seventy-six children with allergic purpura were randomly divided into the treated group (Based on the Western routine therapy of the control group, Kangmin Xiaoban Yin, a kind of TCM decoction, was added for 7-10 days) and the control group. Levels of urinary beta2-microglobulin (beta2-MG) and serum IgA, IgE were measured before and after treatment. And clinical observation on the disappearance time (DT) of abdominal pain, arthralgia and purpura were implemented.</p><p><b>RESULTS</b>The DT of joint swelling, arthralgia, and purpura in the treated group was shorter than those in the control group, showing significant difference (P<0.01). Comparison between groups in urinary beta2-MG and serum IgA and IgE before treatment and 1 week after treatment were insignificantly different (P>0.05), but at 1 month and 6 months after treatment, the level of urinary beta2-MG in the treated group was lower than that in the control group, with significant difference (P<0.05), and levels of serum IgA and IgE at 1 month after treatment in the former were lower than those in the control group, also showing significant difference (P<0.05, P<0.01). Six-month recurreat rate in the treated group was 23.5%, while that in the control group. There was significant difference in comparison in 1/2-year recurrent rate (P<0.01).</p><p><b>CONCLUSION</b>ICWM in treating allergic purpura could reduce the repeated episodes and shorten the hospitalization time, and effectively prevent the renal impairment of the disease.</p>