Free radical reaction and erythrocyte membrane damage in disseminated intravascular coagulation (DIC) caused by endotoxin / 中国病理生理杂志

The effect of free radicals and the mechanism of cell damage in the patho-logical process of endotoxin DIC was studied to elucidate the relationship between freeradicals reaction and erythrocyte membrane injury in DIC induced by endotoxin. Molecu-lar biomechanics, biomembrane chemistry were applied to rabbits in this work. Resultsshowed that there was a significant increase both in RBC membrane lipid peroxides level(0. 285?0. 063, P

The change and the significance of serum lipid peroxidation and red blood cell SOD activity during endotoxin DIC in rabbits / 中国病理生理杂志

In order to understand the change of free radicals in the pathological process of endotoxin DIC, the level of serum lipid peroxides (LPO) and the activity of erythrocyte superoxide dismutase (SOD) were determined by thiobarbituric acid method and pyrogallol method in disseminated intravascular coagulation (DIC) rabbits induced by endotoxin. Results showed that there was a significant increase (P