The imaging manifestation and pathological analysis of intracerebroventricular central neurocytoma / 实用医学杂志

Objective To explore the radiological features of intracerebroventricular central neurocytoma and so as to improve the diagnosis of this disease. Methods Thirty patients with pathologically confirmed intra-cerebroventricular central neurocytoma in Nanfang Hospital in past 7 years were analyzed retrospectively for their clinical,radiological and pathological features combined with literatures review. Results Lesions of central neuro-cytoma located at the Monro's foramen areas,the anterior horns and bodies of lateral ventricles.Twenty eight of the patients underwent MRI(with 4 patients received MRS)and 11 patients underwent CT.All cases revealed unilateral or bilateral hydrocephalus of the lateral ventricles and ventriculomegaly.Plain CT revealed heterogeneous isodensity or slighly high density lesions with multiple cystic degeneration,necrosis and calcification while a few lesions(4 le-sions)showed hemorrhage.Heterogeneous isointense or mild hypointense were demonstrated on T1-weight MRI and heterogeneous isointense or slightly hyperintense on T2-weight MRI.Multiple cystic degeneration(always showed as distinctive "soap bubble sign"), necrosis and calcification could also be found within the tumor. The solid compo-nent of tumor revealed slightly high to high signal intensity on DWI while the cystic and necrosis components showed low signal intensity.Most of the tumors showed mild to moderate enhancement with vessels passing through on contrast scan. All cases with 1H MRS showed with obviously increased in Cho peak and decreased in Cr and NAA peaks.In immunohistochemical assay,most of the tumors revealed positive expressions of Neu-N,Synaptophy-sin, GFAP and hypo-level Ki-67. Conclusions The intracerebroventricular central neurocytoma has some typical imaging manifestations.Comprehensive analysis of CT and MRI can be conducive to preoperative diagnosis and dif-ferential diagnosis with other tumors in the lateral ventricle.

CT findings and misdiagnosis analysis of gistric schwannoma / 实用医学杂志

Objective To explore the CT findings of gistric schwannoma and analyze the misdiagnosis causes to improve the diagnosis accuracy of the disease. Methods The findings of CT imaging in 15 cases with pathologically proved gistric schwannoma were reviewed restrospectively ,and relevant literatures were reviewed. Results In those 15 cases,3 were men,12 were women,the oldest was 61,the youngest was 33,and the medi-an age was 53.10 cases were located in the greater curvature side of gastric body ,2 cases in the gastric cardia ,3 cases in the diatal.14 cases underwent CT plain and contrast-enhanced scanning while 1 case only underwent CT plain. The 15 cases were single,round lumps with equable density. The performance of 14 routine enhancement scan was characterized by mild uniform strengthing of The arterial period ,further Strengthening of the venous phase,and mild prolonged delay. Conclusion The CT fingings of gistric schwannoma has certain characteristics. It usually occurred in gastric body with single type of circular lump and often presents with equable density. Homo-geneous progressive enhancement on dynamic CT is a characteristic finding of gistric schwannoma.

CT findings and misdiagnosis analysis of gistric schwannoma / 实用医学杂志

Objective To explore the CT findings of gistric schwannoma and analyze the misdiagnosis causes to improve the diagnosis accuracy of the disease. Methods The findings of CT imaging in 15 cases with pathologically proved gistric schwannoma were reviewed restrospectively ,and relevant literatures were reviewed. Results In those 15 cases,3 were men,12 were women,the oldest was 61,the youngest was 33,and the medi-an age was 53.10 cases were located in the greater curvature side of gastric body ,2 cases in the gastric cardia ,3 cases in the diatal.14 cases underwent CT plain and contrast-enhanced scanning while 1 case only underwent CT plain. The 15 cases were single,round lumps with equable density. The performance of 14 routine enhancement scan was characterized by mild uniform strengthing of The arterial period ,further Strengthening of the venous phase,and mild prolonged delay. Conclusion The CT fingings of gistric schwannoma has certain characteristics. It usually occurred in gastric body with single type of circular lump and often presents with equable density. Homo-geneous progressive enhancement on dynamic CT is a characteristic finding of gistric schwannoma.

Radiological and clinicopathological analysis of benign fibrous histiocytoma of bone / 实用医学杂志

Objective To explore the imaging radiological and clinicopathological characteristics of benign fibrous histiocytoma (BFH) of bone, in order to improve the imaging diagnostic accuracy of the disease Methods Radiological and clinical data of 16 patients with BFH confirmedbypathology were retrospectively analyzed , and relevant literatures were reviewed. Results The X-ray findings of 14 BFHpatients were osteolytic lesion , expansive destruction of bone,without soft tissue involvement, 10 with residual apophysis,9 with osteosclerosis marginal; CT was performed on 2 patients. Expansive destruction of bone and soft tissue densities were seen inside the loops , 1 case remarkable enhancement of the lesion. MRI was performed on 9 patients and 5 cases showed long T1 and T2 signal intensity; 1case showed equal T1 and long T2 signal intensity in cystic part and equal T1 and T2 signal intensity in the solid part. One patient had pathological fracture, and the surrounding soft tissue invaded, showing equal T1 and long T2 signal intensity. Two lesions located at spinous process of cervical vertebra , showing long T1 short T2 and equal T1 and T2 signal intensity. Linear low signal separation shadow in T1 and T2 could be seen in 6 cases. Long T1 and short T2 sclerotic ring were seen in 4 cases. Solid part of tumor and linear separator were obviously enhanced. Conclusions The radiological findings of benign fibrous histioeytoma of bone indicate some characteristics. The combination with X-ray , CT and MRI examination is helpful to improve the diagnostic accuracy of the disease before operation.

CT manifestations and pathologic features of mediastinal primary small cell neuroendocrine carcinoma / 医学研究生学报

Objective Mediastinal primary small cell neuroendocrine carcinoma ( MPSCNC) is a rare neoplasm of high ma-lignant potential mostly affecting elderly and middle-aged males, which has a high rate of misdiagnosis because of its unidentified histo-genesis and lack of obvious characteristic imaging findings .This study was to investigate the CT findings and pathologic features of MP-SCNC, so as to improve the recognition and diagnostic accuracy of the disease . Methods We retrospectively analyzed the imaging and clinicopathologic data about 4 cases of pathologically confirmed MPSCNC and reviewed relevant literature . Results Of the 4 tumors, 2 were located in the anterior-middle-superior mediastinum , 1 in the anterior-superior mediastinum , and the other in the mid-dle-superior mediastinum .Three of them exhibited irregular shape , unclear boundary , and inhomogeneous density , with low-density cyst degeneration and necrosis , of which two had scattered punctate calcifications .Enhanced scanning revealed moderate uneven en-hancement in 3 cases and ring-shaped enhancement the other .Pathological findings showed small tumor cells with marked pleomor-phism, little cytoplasm, pale chromatin, inconspicuous or absent nucleoli , and obvious mitotic figures.Immunochemistry manifested positive CgA, Syn, and CK in all the 4 cases, positive NSE, CD56, and Ki-67 in 3 cases, and positive epithelial membrane antigen in 1. Conclusion A tumor located in the anterior-middle mediastinum with scattered punctate calcifications and compressing or inva-ding the adjacent mediastinal structures should be suspected as a small cell neuroendocrine carcinoma . However , definite diagnosis should be based on histopathologic and immunohistochemical exami-nations .

MSCT Imaging Findings in Anterior Mediastinal Primary Malignant Tumors / 实用医学杂志

Objective To investigate the MSCT imaging of anterior mediastinal primary malignant tumors , and to improve the accuracy of diagnosis. Methods The imaging and clinical data of forty-five patients with anterior mediastinal primary malignant tumors were retrospectively analyzed. Results Among all forty-five cases, there were seventeen thymic carcinomas , and cystic and necrotic earas were seen in all cases. Fourteen were malignant lymphomas with a single irregular soft tissue mass or multiple merged nodules. There were enlarge lymph nodes around the tumors and (or) in other parts of the body. Twelve cases were malignant germinomas, the levels of rinary human chorionic gonadotropin (HCG) or blood armour fetuin (AFP) were abnormal in ten cases, and calcifications were seen in four cases and fat composition was observed in three cases. One malignant solitary fibrous tumor was observed on the left side of the anterior-superior mediastinum with cystic degeneration and necrosis. One was neuroendocrine carcinoma with clear boundary , cystic degeneration and necrosis , after enhanced scanning , it showed ring-shaped reinforcement. Conclusion Anterior mediastinal primary malignant tumors have certain characteristics of MSCT findings , in combination with clinical information , which can help the diagnosis and efficacy evaluation.