ABSTRACT
Objective To explore the clinical curative effect of cerebral angio spasm after aneurysm rupture subarachmoid hemorrhage by Fasudil, Methods The clinical data of cerebral angio spasm after aneurysm rupture subarachnoid hemorrhage were retrospectively analyzed, which was divided into detection group and control group.Results The GCS score of detection group was better than control group;the average blood flow rate of arteria cerebri media after curing in detection group the difference had statistical significance( all P ＜0. 05 ). The mutilation rate、rate of death of detection group were lower than control goup, the difference had statistical significance ( P ＜ 0. 05 ).Conclusion The clinical curative effect was good of cerebral angio spasm after aneurysm rupture subarachnoid hemorrhage by Fasudil, and prognosis was good.
ABSTRACT
Objective To investigate the metabolic characteristics,clinic values of different tissues in benign prostatic hyperplasia by correlating MR spectroscopy(MRS)with whole pathologic sections.Methods MRS presentation was studied in 16 patients with benign prostatic hyperphsia.The peak values of citrate,choline and creatine were measured,and the mtios of(choline+creatine)/citrate(cc/c)were obtained.After suprapubic transvesical prostatectomy,the specimens of whole pathologic sections were observed.The values of cc/c of different pathologic types were compared statistically with One.way-ANOVA and t test. Results MRS results were obtained in 578 units,which included 233 glandular tissue units.130 matrical tissue units.165 mixed tissue units and 50 tissue units around urethra.The ratios of (choline+creatine)/citrate of glandular,matrical.mixed tissues and units around urethra were 0.59±0.29.1.23±0.38.0.80±0.27 and 0.68±0.33(F=3.49.P＜0.05).The t tests were carried out between every two tissues.The t valUes between glandular tissues and matrical.mixed tissues were 19.60 and 7.09.P＜0.05:the t values between matrical tissues and mixed tissues.units around urethra were 13.22 and 9.42,P＜0.05;the t valUes between mixed tissues and units around urethra was 9.42,P＜0.05.Condusions,The ratios of cc/c ofthree prostate tissues were different in MRS.The metabolic characteristic of the units around urethra Was near to glandular units.MRS may be valuable to the distinctive diagnoses of prostate diseases.
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Objective To study the effects of home nursing on patients with benign prostatic hyperplasia. Methods One hundred and eighty patients with benign prostatic hyperplasia meeting our experimental conditions were selected. They were divided into experimental group and comparative group. The experimental group had 82 cases and the average age was 68.5 ?1.2 yrs, the comparative group had 98 cases and the average age was 66.8?0.8. The first prevalence survey was carried out including history of past illnesses, international prostate symptom score, quality of life assessment, customs of life, habits of diet, circumstances of medicine and statuses of psychology. The patients of experimental group received home nursing including psychology nursing, directions of medication, reformations of customs in life and diet, strength in body exercise and kinesitherapy. The patients of comparative group did not receive any nursing measures. After two, four, six months, three prevalence surveys were carried out. At the end of each time, the data were collected and statistical treatments were processed. Results The IPSS rates of improvement in experimental group were 14.6% , 31.7% , and 52.4% . The QOL rates of improvement in experimental group were 12.2% , 34.2% , 57.3% . The IPSS rates of improvement in comparative group were 4.0%, 10.0%, 18.4%. The QOL rates of improvement in comparative group were 3.1%, 13.3%, 16.3%. There was statistical differences between two groups in international prostate symptom score and quality of life assessment (P
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Objective The paper described a convenient and sensitive radioirnmunoassav method which can be used to measure the amount of morphine in a single hair. Method Succinvl-eggalbumin-morphine was used as immunogen to immunize New Zealand rabbits for obtaining high quality antiserum. The morphine- labeled with Iodine-125 was purified by HPLC. The radioimmunoassay method was established and the amount of morphine in a single hair was detected. Results The affinity constant of antibody is 3.25 ? 10~11L/M. The radiochemical purity of I-mophine is 95% and the specific radioactivity is 112?Ci/?g. The detection limit for morphine (3SD from zero-dose binding) is 0.01ng/ml. Five normai person's single hair and five addict's were detected . The length of these specimens is 9-24cm and the weight of them 0.7- 2. 1mg. The amount of morphine in the hair of normai person is 1. 75 ? 0.37ng/mg (x ? 5) and that of the addictos'is 471 ?204ng/mg (x ? s). Conclusion This method can be employed for accurate mea-surement of the amount of morphine in a single hair and the result can be adopted to indicate the probability of illicit-drug use.