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Objective@#To investigate clinical characteristics and treatment of phytophotodermatitis due to ingesting Chenopodium album.@*Methods@#This study included 11 patients with phytophotodermatitis caused by ingesting Chenopodium album collected from Department of Dermatology, Affiliated Hospital of Jining Medical University from 2013 to 2017. The patients′ general information, clinical manifestations, laboratory test results, treatment and prognosis were retrospectively analyzed.@*Results@#All the 11 patients were female, and their age ranged from 45 to 62 years. They all had a history of ingesting Chenopodium album and exposing to sunlight within 1 - 2 days prior to the disease onset. Clinical manifestations included symmetrically distributed, painful and pruritic, nonpitting, swelling erythema on the face and back of both hands and at sunexposed sites of forearms, with a tense and bright surface. Increased white blood cell counts were observed in 6 patients, and increased eosinophil counts in 1. All of the 11 patients were treated with systemic methylprednisolone, loratadine, ebastine, spironolactone, furosemide and omeprazole as well as topical agents, 2 also received human immunoglobulin treatment, and 3 were also treated with oral ibuprofen and codeine for painful lesions. Ten patients received obvious improvement and were discharged after 7 - 10 days of treatment, and no pigmentation or scars were observed after 1-year follow-up. Skin necrosis occurred on the back of both hands in 1 patient after 7-day treatment, and scars remained in the patient after follow-up of half a year.@*Conclusions@#Chenopodium album-induced phytophotodermatitis commonly manifests as swelling erythema on the exposed body sites. After confirmed diagnosis, Chenopodium album ingestation and sunlight exposure should be avoided, and timely antianaphylactic treatment should be considered to effectively control the disease.
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Objective To investigate clinical characteristics and treatment of phytophotodermatitis due to ingesting Chenopodium album.Methods This study included 11 patients with phytophotodermatitis caused by ingesting Chenopodium album collected from Department of Dermatology,Affiliated Hospital of Jining Medical University from 2013 to 2017.The patients' general information,clinical manifestations,laboratory test results,treatment and prognosis were retrospectively analyzed.Results All the 11 patients were female,and their age ranged from 45 to 62 years.They all had a history of ingesting Chenopodium album and exposing to sunlight within 1-2 days prior to the disease onset.Clinical manifestations included symmetrically distributed,painful and pruritic,nonpitting,swelling erythema on the face and back of both hands and at sunexposed sites of forearms,with a tense and bright surface.Increased white blood cell counts were observed in 6 patients,and increased eosinophil counts in 1.All of the 11 patients were treated with systemic methylprednisolone,loratadine,ebastine,spironolactone,furosemide and omeprazole as well as topical agents,2 also received human immunoglobulin treatment,and 3 were also treated with oral ibuprofen and codeine for painful lesions.Ten patients received obvious improvement and were discharged after 7-10 days of treatment,and no pigmentation or scars were observed after 1-year follow-up.Skin necrosis occurred on the back of both hands in 1 patient after 7-day treatment,and scars remained in the patient after follow-up of half a year.Conclusions Chenopodium album-induced phytophotodermatitis commonly manifests as swelling erythema on the exposed body sites.After confirmed diagnosis,Chenopodium album ingestation and sunlight exposure should be avoided,and timely antianaphylactic treatment should be considered to effectively control the disease.
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Through the two-step method FST group and FST6 group both can successfully induce DC into mature functions;the induction in FST6 group is more efficient.
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Objective To assess the curative effect of endoscopic resection for patients with duode-nal bulb carcinoid.Methods Data of 17 patients with duodenal bulb submucosal tumor who underwent en-doscopic dissection in our department and confirmed as duodenal bulb carcinoid by postoperative pathology from Jun 2009 to Jun 2012 were retrospectively analyzed.Seventeen patients included 1 1 men and 6 women with the mean age of 36. 3 ±8. 4.Results All patients underwent preoperative diagnosis of endoscopic ultrasonography(EUS).Four cases were diagnosed as heterotopic pancreas and 13 cases carcinoid.The size of tumor was from 4 to 10 millimeter.Cap-assisted endoscopic mucosal resection (EMR-C)were used in all patients successfully.No complications were found during or after the operation.Postoperative pathology con-firmed 6 cases of duodenal bulb carcinoid.The accuracy of EUS preoperative diagnosis was 76. 5%.The average follow-up time was 20. 5 ±12. 4 months.Metastases and recurrence had not been found.Conclusion EUS can confirm the invasive depth of duodenal submucosal tumors and estimate the indication of endo-scopic excision.EUS can not give a preoperative qualitative diagnosis of duodenal submucosal tumors.Endo-scopic hyaline cap excision is a safe and sufficient method for duodenal bulb carcinoid.