ABSTRACT
Sciatic neurectomy was performed on the right limb in 30 rats divided into three groups. On the first postoperative days, stainless steel capacitor plates were applied parallel to each other over the midtibial region of the right, neurectomized limb m each animal in the latter two groups, which were stimulated continuously with a 60kHz sinawave signal delivering 5-10V from peak to peak. The first group was served as controls and received no electrical stimulation. At the completion of 12d of electrical stimulation, all rats were sacrificed. A statistically significant enhancement of wet weight, dry weight, ashed weight, ultimate strength and bone density occurred in the stimulated, denervated tibiae of the experimental animals compared with the nonstimulated, denervated tibiae of the control animals. The results show that a sciatic neurectomized osteoporosis was prevented in the tibiae by a capacitively coupled electrical field.
ABSTRACT
In this study Na2HPO4-Ca(NO3)2 system was used to synthesize hydroxyapatite (HA). Its synthetical method was simple and low in cost. With the physical-chemical characteristic observation and the animal experimentit was proved that HA was pure, with pores ranging from 20 to 200 ?m in diameter.The chemical structure of HA was similar to that of inorganic part of bones.An investigation of the histological changes and osteogenetic effectiveness of HA implanted was conducted and the mechanism of HA osteogenetic effectiveness is discussed. The study will provide scientific basis for the clinical use of HA as bone graft substitute.
ABSTRACT
The traditional treatment for primary malignant tumors involving the innominate bone is hemi-pelvictomy.In recent years, under the control of chemotherapy or radiation, partial or complete resection of innominate bone with lower extremities maintained has been reported.Since 1983, five patients in our hospital have undergone resection of hemi-pelves and femoral heads, and have been inserted by titanium-alloy hemi-pelves and total hip prostheses.The operations were uneventful.Among the five patients, the first and the second were diagnosed as condrosar-coma. Before and after operations, the two patients were treated with a large dosage of chemotherapy and had no reactions.During the follow-up for two years and a half. They were pain-free in affected limbs and could walk with canes.The other three patients diagnosed as giant-cell tumors were followed up from half a year to one year, and they all could walk with crutches.Based on the five cases, we think that in some very carefully selected cases, a limb-saving procedure-inserting a prosthesis after performing hemi-pelvictomy-can lead to a good function and maintain the limb length.
ABSTRACT
Our experiment aims to compare the effects of "energy-containing lactated Ringer's solution"(EL-RS) with those of "lactated Ringer's solution" (LRS) as an initial resuscitation fluid for the treatment of traumatic shock in rabbits. Deep shock animal models were produced in 74 adult rabbits using the method of pincers pressure and Wiggers' hemorrhagic shock method to produce crush injury of the soft tissue on the thigh and comminuted fracture of the femur. Results showed that blood pressure of the experimental group rose more rapidly than control group and the survival time of the former were longer than the later. The lowering of serum lactate and blood pH etc. showed a similar difference. It is suggested that ELRS is more efficient than LRS for the treatment of traumatic shock in rabbits.
ABSTRACT
Benign or low-grade malignant tumor of bones neighbouring a joint can be treated by segmental resection and the use of an allograft for reconstruction. Fourteen patients have been treated in this way since 1977, with success in 12 cases and failure in 2 because of infection.Allograft was obtained from fresh cadaver and stored in deep-frozen state (-170C). Within 3 weeks to 6 months, the biological vigor of the bone tissue could be retained and its antigenicity destroyed, so that no immunological reaction took place after replacing the joint and the allograft survived.Eleven patients have been followed up from one and one-half years to five years In the 7 cases with giant-cell tumor at the proximal end of tibia, their range of movement has been attained around 90 degrees. Of the two patients with os-teogenic sarcoma, one has been followed up for one and a half years, and the other for three years. There appears no evidence of local recurrence or distant metastasis in both. The affected limbs are all capable of weight-bearing and locoma-tion.