ABSTRACT
Objective To detect the serum levels ofγ-glutamyltransferase(GGT),α-L-fucosidase(AFU),des-gamma-carbory prothrombin(DCP),and alpha fetoprotein(AFP) hepato carcinoma patients,and explore its clini-cal predictive value in the diagnosis of hepatocarcinoma .Methods GGT and AFU was measured by velocity method , radioimmunoassay was used in DCP measurement ,and ELISA assay was adopted to measure AFP .The levels of serum GGT,AFU,DCP and AFP were measured in 47 patients with primary hepatic carcinoma ,35 patients with secondary liver cancer ,and 56 normal people .All results were analyzed by statistic method .Results The positive rates of serum GGT,AFU,DCP and AFP in primary hepatic carcinoma and secondary liver cancer were 89.4%,83.0%,74.5%, 76.6%and 82.9%,48.6%,68.6%,62.9%,respectively,which were higher than those of normal people (χ2GGT =11.05,χ2AFU =7.35,χ2DCP =8.34,χ2AFP =14.58,all P<0.01).Combined detection of the four index ,the positive rates were 95.7%and 88.6%,which was higher than that of normal people (χ2 =10.13,P<0.05).Conclusion Com-bined detection the levels of serum GGT ,AFU,DCP and AFP can help the early diagnosis of hepatic carcinoma .